| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5254735 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA5254736 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA5254737 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal current at -80 mV holding potential under less potent phase in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA5254751 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5254752 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA5254753 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA5254754 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA5254755 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 100 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA5254756 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 300 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA5254757 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA5254758 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA5254759 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA5254760 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 14. | ALA5254761 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 100 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA5254762 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 300 nM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5254763 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 1 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA5254764 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 3 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA5254765 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 10 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA5254766 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as maximal efficacy at -80 mV holding potential at 30 uM in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA5254701 | B | Positive allosteric modulation of rat recombinant GABAA alpha1beta3alpha1-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-induced current amplitude at -80 mV holding potential in presence of GABA EC1 to 1.5 by two-electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature |
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