| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4195494 | B | Inhibition of IKK-alphabeta in mouse RAW264.7 cells assessed as reduction in LPS-induced IKK-alphabeta phosphorylation at 1 to 10 uM preincubated for 1 hr followed by LPS stimulation for 15 to 30 mins by Western blot method | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4834008 | B | Inhibition of IKKalpha/beta in LPS-stimulated mouse RAW264.7 cells assessed as decrease in IkappaB degradation at 3 uM preincubated for 2 hrs followed by LPS stimulation for 10 mins by immunoblotting assay | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 3. | ALA4834009 | B | Inhibition of IKKalpha/beta in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of NFkB p65 nuclear translocation at 3 uM preincubated for 2 hrs followed by LPS stimulation for 30 mins by immunoblotting assay | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 4. | ALA4834014 | B | Inhibition of IKKalpha/beta phosphorylation in LPS-induced mouse RAW264.7 cells incubated for 2 hrs followed by LPS stimulation and measured after 5 mins by immunoblotting assay | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 5. | ALA4834016 | B | Inhibition of IKKalpha/beta in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of IkappaB alpha phosphorylation at 3 uM preincubated with DTT for 30 mins and later incubated with cells for 2 hrs followed by LPS stimulation for 5 mins by immunoblot anlaysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 6. | ALA4834017 | B | Inhibition of IKKalpha/beta in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of IkappaB alpha degradation at 3 uM preincubated with DTT for 30 mins and later incubated with cells for 2 hrs followed by LPS stimulation for 10 mins by immunoblot anlaysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 7. | ALA4834018 | B | Inhibition of IKKalpha/beta in LPS-stimulated mouse RAW264.7 cells assessed as inhibition of IkappaB alpha phosphorylation preincubated for 2 hrs followed by LPS stimulation for 5 mins by immunoblot anlaysis | Mus musculus | 1 | tissue-based format | Scientific Literature | ||
| 8. | ALA5124662 | B | Inhibition of IKKalpha/beta phosphorylation at Ser176/180 in LPS-induced mouse C8D1A cells at 0.75 to 3 uM pretreated for 4 hrs followed by LPS stimulation measured after 24 hrs by Western blotting analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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