| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4270190 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of nuclear translocation at 10 uM after 6 hrs by DAPI staining based fluorescence microscopic analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4270191 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of ARE by measuring increase in HO-1 expression after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4270192 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of ARE by measuring increase in HO-1 expression at 10 uM after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4670770 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4670771 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4670772 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4670774 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4670775 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4670776 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4670796 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4670797 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4670798 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4670800 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4670801 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4670802 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA5260322 | F | Invivo inhibition of Nrf2-Keap1 Kelch domain protein-protein interaction in po dosed Wistar rat kidney assessed as increase in HO-1 protein level incubated for 6 hrs by ELISA assay | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5260323 | F | Invivo inhibition of Nrf2-Keap1 Kelch domain protein-protein interaction in po dosed Wistar rat kidney assessed as increase in HO-1 protein level by measuring fold change at 30 mg/kg incubated for 6 hrs by ELISA assay relative to control | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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