# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4270190 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of nuclear translocation at 10 uM after 6 hrs by DAPI staining based fluorescence microscopic analysis | Rattus norvegicus | 1 | ALA4266049 | cell-based format | Scientific Literature | |
2. | ALA4270191 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of ARE by measuring increase in HO-1 expression after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4266049 | cell-based format | Scientific Literature | |
3. | ALA4270192 | B | Inhibition of Keap1/Nrf2 signaling in rat PC12 cells assessed as induction of ARE by measuring increase in HO-1 expression at 10 uM after 24 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4266049 | cell-based format | Scientific Literature | |
4. | ALA4670770 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
5. | ALA4670771 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
6. | ALA4670772 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM mRNA expression incubated for 12 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
7. | ALA4670774 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
8. | ALA4670775 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
9. | ALA4670776 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM expression incubated for 12 hrs by Western blot analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
10. | ALA4670796 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
11. | ALA4670797 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
12. | ALA4670798 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM mRNA expression at 10 uM incubated for 4 to 24 hrs by Trizol reagent based qRT-PCR analysis | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
13. | ALA4670800 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of HO1 expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
14. | ALA4670801 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of NQO1 expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
15. | ALA4670802 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in rat H9c2 cells assessed as upregulation of GCLM expression at 10 uM incubated up to 24 hrs by Western blot | Rattus norvegicus | 1 | ALA4665802 | cell-based format | Scientific Literature | |
16. | ALA5260322 | F | Invivo inhibition of Nrf2-Keap1 Kelch domain protein-protein interaction in po dosed Wistar rat kidney assessed as increase in HO-1 protein level incubated for 6 hrs by ELISA assay | Rattus norvegicus | 1 | ALA5257130 | organism-based format | Scientific Literature | |
17. | ALA5260323 | F | Invivo inhibition of Nrf2-Keap1 Kelch domain protein-protein interaction in po dosed Wistar rat kidney assessed as increase in HO-1 protein level by measuring fold change at 30 mg/kg incubated for 6 hrs by ELISA assay relative to control | Rattus norvegicus | 1 | ALA5257130 | organism-based format | Scientific Literature |