# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4219433 | B | Induction of cereblon-mediated CK1alpha (unknown origin) degradation in at 0.0005 to 10 uM after 4 hrs by cell-based chemiluminescent assay | Homo sapiens | 1 | ALA4219026 | cell-based format | Scientific Literature | |
2. | ALA4366976 | B | Inhibition of CRBN-mediated CK1alpha degradation in human OPM2 cells measured after 24 hrs by Western blot analysis | Homo sapiens | 25 | ALA4364285 | cell-based format | Scientific Literature | |
3. | ALA5037089 | B | PROTAC activity at CRBN/CK1alpha in human MV4-11 cells assessed as induction of CK1alpha degradation at 1 uM measured after 4 hrs by tandem mass tag mass spectrometry analysis | Homo sapiens | 1 | ALA5036322 | cell-based format | Scientific Literature | |
4. | ALA5041518 | B | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 200 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
5. | ALA5041522 | B | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 1 microM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 4 | ALA5038641 | cell-based format | Scientific Literature | |
6. | ALA5041531 | B | Protac activity at CRBN/CK1alpha in human MM1.S cells assessed as induction of CK1alpha degradation at 40 nM measured after 4 hrs by Immunoblotting analysis | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
7. | ALA5041535 | B | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 250 microM measured after 4 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature | |
8. | ALA5041544 | B | Protac activity at CRBN/CK1alpha in human MOLT-4 cells assessed as induction of CK1alpha degradation at 1 microM measured after 5 hrs by proteome mass spectrometry | Homo sapiens | 1 | ALA5038641 | cell-based format | Scientific Literature |