| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3579717 | B | Activation of Keap1/Nrf2/ARE pathway in mouse Hepa-1c1c7 cells assessed as double induction of NQO1 specific activity after 48 hrs by bicinchoninic acid assay | Mus musculus | 16 | cell-based format | Scientific Literature | ||
| 2. | ALA3859578 | B | Inhibition of Keap1-Nrf2 interaction in mouse RAW264.7 cells assessed as induction of NQO1 gene expression at 2 to 10 uM after 5 hrs by real time PCR method | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 3. | ALA4048125 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in MEF assessed as increase in Nrf2 activation mediated NQO1 mRNA level at 100 uM after 4 hrs by qRT-PCR method | Mus musculus | 1 | assay format | Scientific Literature | ||
| 4. | ALA4048126 | B | Inhibition of Keap1-Nrf2 protein-protein interaction in MEF assessed as increase in Nrf2 activation mediated NQO1 mRNA level at 10 uM after 4 hrs by qRT-PCR method | Mus musculus | 1 | assay format | Scientific Literature | ||
| 5. | ALA4141612 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of NQO1 mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4141613 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of HO-1 mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4141614 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of GCLM mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4141615 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in NQO1 levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4141616 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in HO-1 levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4141617 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in GCLM levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4141632 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of NQO1 mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4141633 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of HO1 mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4141634 | B | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of GCLM mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4143357 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Srxn1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4143358 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Hmox1 expression level at 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4143359 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as downregulation of Socs3 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4143360 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as downregulation of Rasgef1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4143361 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Txrdn1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4143362 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Prdx1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4143363 | B | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Sqstm1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | cell-based format | Scientific Literature |
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