# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3579717 | Binding | Activation of Keap1/Nrf2/ARE pathway in mouse Hepa-1c1c7 cells assessed as double induction of NQO1 specific activity after 48 hrs by bicinchoninic acid assay | Mus musculus | 16 | ALA3576826 | cell-based format | Scientific Literature | |
2. | ALA3859578 | Binding | Inhibition of Keap1-Nrf2 interaction in mouse RAW264.7 cells assessed as induction of NQO1 gene expression at 2 to 10 uM after 5 hrs by real time PCR method | Mus musculus | 5 | ALA3856271 | cell-based format | Scientific Literature | |
3. | ALA4048125 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in MEF assessed as increase in Nrf2 activation mediated NQO1 mRNA level at 100 uM after 4 hrs by qRT-PCR method | Mus musculus | 1 | ALA4043278 | assay format | Scientific Literature | |
4. | ALA4048126 | Binding | Inhibition of Keap1-Nrf2 protein-protein interaction in MEF assessed as increase in Nrf2 activation mediated NQO1 mRNA level at 10 uM after 4 hrs by qRT-PCR method | Mus musculus | 1 | ALA4043278 | assay format | Scientific Literature | |
5. | ALA4141612 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of NQO1 mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
6. | ALA4141613 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of HO-1 mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
7. | ALA4141614 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of GCLM mRNA expression at 0.1 to 10 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
8. | ALA4141615 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in NQO1 levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | ALA4138151 | cell-based format | Scientific Literature | |
9. | ALA4141616 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in HO-1 levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | ALA4138151 | cell-based format | Scientific Literature | |
10. | ALA4141617 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as increase in GCLM levels up to 10 uM after 8 hrs by Western blot analysis | Mus musculus | 2 | ALA4138151 | cell-based format | Scientific Literature | |
11. | ALA4141632 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of NQO1 mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
12. | ALA4141633 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of HO1 mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
13. | ALA4141634 | Binding | Inhibition of Keap1/Nrf2 protein-protein interaction in mouse RAW264.7 cells assessed as upregulation of GCLM mRNA expression at 1 uM after 10 hrs by quantitative real-time-PCR analysis | Mus musculus | 1 | ALA4138151 | cell-based format | Scientific Literature | |
14. | ALA4143357 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Srxn1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
15. | ALA4143358 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Hmox1 expression level at 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
16. | ALA4143359 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as downregulation of Socs3 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
17. | ALA4143360 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as downregulation of Rasgef1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
18. | ALA4143361 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Txrdn1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
19. | ALA4143362 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Prdx1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature | |
20. | ALA4143363 | Binding | Activation of Keap1/Nrf2 in mouse LPS-induced RAW264.7 cells assessed as increase in Sqstm1 expression level at 4 to 12 uM pretreated for 1 hr followed by LPS addition measured after 30 to 180 mins | Mus musculus | 1 | ALA4138226 | cell-based format | Scientific Literature |