| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4150533 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 0.1 to 1 uM measured after 6 to 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4150534 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 to 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4150535 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 0.1 to 10 uM measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4150536 | B | Induction of CRBN-mediated CDK8 degradation in wild-type human MOLT4 cells at 5 uM measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4150538 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells up to 10 uM measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4150539 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of proteasome inhibitor bortezomib by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4150540 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of neddylation inhibitor MLN4924 by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4150541 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of N-((3S,17S)-17-(isoquinolin-7-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl)-Nmethyl-1-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12-tetraoxapentadecan-15-amide by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4150542 | B | Induction of CRBN-mediated CDK8 degradation in human Jurkat cells at 1 uM measured after 6 hrs in presence of lenalidomide by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4150544 | B | Induction of CRBN-mediated CDK8 degradation in wild-type human Jurkat cells at 1 to 10 uM measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4150545 | B | Induction of CRBN-mediated CDK8 degradation in wild-type human Jurkat cells at 20 uM measured after 24 hrs by immunoblot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4822287 | B | Protac activity at CDK8/CRBN in human HEK293 cells assessed as degradation of CDK8 at 0.01 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4822296 | B | Protac activity at CDK8/CRBN in human HEK293 cells assessed as degradation of CDK8 at 1 uM measured upto 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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