| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4124656 | B | Induction of CRBN ubiquitin ligase-mediated HDAC4 degradation in human MCF7 cells assessed as decrease in HDAC4 levels at 5 uM after 12 hrs by immunoblotting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 2. | ALA4124661 | B | Induction of CRBN ubiquitin ligase-mediated HDAC4 degradation in human MCF7 cells assessed as decrease in HDAC4 levels at 10 uM after 12 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4312374 | B | Protac activity at CRBN/HDAC4 in human MM1S cells assessed as HDAC4 degradation measured after 6 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4312408 | B | Protac activity at CRBN/HDAC4 in human MM1S cells assessed as HDAC4 degradation at 100 nM measured after 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4312409 | B | Protac activity at CRBN/HDAC4 in human MM1S cells assessed as HDAC4 degradation at 100 nM measured after 6 hrs in presence of proteasome inhibitor bortezomib by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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