# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4124655 | B | Induction of CRBN ubiquitin ligase-mediated HDAC2 degradation in human MCF7 cells assessed as decrease in HDAC2 levels at 5 uM after 12 hrs by immunoblotting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
2. | ALA4124660 | B | Induction of CRBN ubiquitin ligase-mediated HDAC2 degradation in human MCF7 cells assessed as decrease in HDAC2 levels at 10 uM after 12 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4124675 | B | Induction of CRBN ubiquitin ligase-mediated HDAC2 degradation in human MCF7 cells assessed as increase in acetylated H3 levels at 2 uM after 12 hrs by immunoblotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA5137987 | B | PROTAC activity at CRBN/HDAC2 (unknown origin) by cell based assay | Homo sapiens | 1 | cell-based format | Scientific Literature |