# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4219274 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 1 nM after 3 hrs in presence of NAE inhibitor MLN4924 by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
2. | ALA4219284 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 1 nM after 3 hrs in presence of proteosome inhibitor MG-132 by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
3. | ALA4219287 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 1 nM after 3 hrs in presence of BET inhibitor 4-((3-Cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino)-7-(3,5-dimethylisoxazol-4-yl)-6-methoxy-N-methyl-9H-pyrimido[4,5-b]-indole-2-carboxamide by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
4. | ALA4219290 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 1 nM after 3 hrs in presence of cereblon inhibitor lenalidomide by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
5. | ALA4219297 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at at 0.1 nM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
6. | ALA4219300 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 30 to 1000 nM after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
7. | ALA4219302 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 30 to 1000 nM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
8. | ALA4219304 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 100 to 300 nM after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
9. | ALA4219308 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 30 to 300 nM after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
10. | ALA4219310 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells after 3 hrs by Western blot method | Homo sapiens | 4 | ALA4219021 | cell-based format | Scientific Literature | |
11. | ALA4219314 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 3 to 10 nM after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
12. | ALA4219344 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human RS4:11 cells at 3 to 30 nM after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219021 | cell-based format | Scientific Literature | |
13. | ALA4219348 | B | Induction of cereblon/cullin 4A-mediated BRD3 degradation in human MOLM13 cells after 3 hrs by Western blot method | Homo sapiens | 2 | ALA4219021 | cell-based format | Scientific Literature | |
14. | ALA4382976 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells in assessed as BRD3 degradation by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature | |
15. | ALA4382979 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells in assessed as BRD3 degradation at 0.1 nM after 3 hrs by Western blot analysis | Homo sapiens | 3 | ALA4382197 | cell-based format | Scientific Literature | |
16. | ALA4382995 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells assessed as BRD3 degradation at 10 pM after 3 hrs by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature | |
17. | ALA4382996 | B | Protac activity at cereblon/cullin 4A/BRD3 in human MV4-11 cells assessed as BRD3 degradation at 10 pM after 3 hrs by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature | |
18. | ALA4383003 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells assessed as BRD3 degradation at 0.5 nM after 3 hrs by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature | |
19. | ALA4383006 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells assessed as BRD3 degradation at 0.5 nM after 3 hrs in presence of lenalidomide by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature | |
20. | ALA4383009 | B | Protac activity at cereblon/cullin 4A/BRD3 in human RS4:11 cells assessed as BRD3 degradation at 0.5 nM after 3 hrs in presence of neddylation inhibitor MLN4924 by Western blot analysis | Homo sapiens | 1 | ALA4382197 | cell-based format | Scientific Literature |