# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4219632 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells after 16 hrs by Western blot method relative to control | Homo sapiens | 33 | ALA4219031 | cell-based format | Scientific Literature | |
2. | ALA4219633 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells after 16 hrs by Western blot method | Homo sapiens | 33 | ALA4219031 | cell-based format | Scientific Literature | |
3. | ALA4219634 | B | Induction of VHL-mediated TBK1 degradation in human A549 cells harboring K-Ras mutant at 100 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
4. | ALA4219636 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells at 0.1 to 1 uM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
5. | ALA4219638 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells at 100 nM after 16 hrs in presence of (2S,4R)-1-((S)-2-acetamido-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
6. | ALA4219639 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells at 100 nM after 16 hrs in presence of proteosome inhibitor carfilzomib by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
7. | ALA4219644 | B | Induction of VHL-mediated TBK1 degradation in human H23 cells harboring K-Ras mutant at 100 to 300 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
8. | ALA4219645 | B | Induction of VHL-mediated TBK1 degradation in human H1792 cells harboring K-Ras mutant at 100 to 300 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
9. | ALA4219646 | B | Induction of VHL-mediated TBK1 degradation in human H2110 cells harboring wild-type K-Ras at 100 to 300 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
10. | ALA4219647 | B | Induction of VHL-mediated TBK1 degradation in human HCC827 cells harboring wild-type K-Ras at 100 to 300 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
11. | ALA4219653 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells at 100 nM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
12. | ALA4219654 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells at 1 uM after 16 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature | |
13. | ALA4219655 | B | Induction of VHL-mediated TBK1 degradation in human Panc02.13 cells assessed as decrease in Poly(I:C)-induced in IRF3 phosphorylation at 100 nM preincubated for 16 hrs followed by Poly I:C addition measured after 3 hrs by Western blot method | Homo sapiens | 1 | ALA4219031 | cell-based format | Scientific Literature |