# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4219515 | B | Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD3 for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 24 hrs by Western blotting method | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
2. | ALA4219521 | B | Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD3 for protein degradation by proteasome by measuring drug level causing 50% cellular protein depletion incubated for 24 hrs by Western blotting method relative to control | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
3. | ALA4219532 | B | Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD3 for protein degradation by proteasome at 30 to 10000 nM incubated for 24 hrs by Western blotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
4. | ALA4219536 | B | Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD3 for protein degradation by proteasome at 1 to 10 uM incubated for 24 hrs by Western blotting method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4219540 | B | Proteolysis targeting chimera activity in human HeLa cells assessed as induction of VCB-mediated delivery of BRD3 for protein degradation by proteasome at 1 to 10 uM incubated for 6 hrs by Western blotting method | Homo sapiens | 2 | cell-based format | Scientific Literature |