#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4257019	B	Binding affinity to N-terminal GST tagged CNK PH domain (unknown origin) by SPR spectroscopy	Homo sapiens	21	ALA4257006	assay format	Patent Bioactivity Data
2.	ALA4257022	B	Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) at 50 uM by SPR spectroscopy	Homo sapiens	19	ALA4257006	assay format	Patent Bioactivity Data
3.	ALA4257039	B	Inhibition of CNKSR1 in human NSCLC cells expressing mutant KRAS assessed as potentiation of erlotinib-induced inhibition of cell growth incubated for 72 hrs by MTS assay	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
4.	ALA4257040	B	Inhibition of CNKSR1 in human NCI-H1792 cells expressing mutant KRAS assessed as inhibition of active RalA protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
5.	ALA4257041	B	Inhibition of CNKSR1 in human NCI-H1792 cells expressing mutant KRAS assessed as inhibition of active RalB protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
6.	ALA4257042	B	Inhibition of CNKSR1 in human NCI-H1792 cells expressing mutant KRAS assessed as inhibition of active Rho protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
7.	ALA4257043	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as inhibition of active RalA protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
8.	ALA4257044	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as inhibition of active RalB protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
9.	ALA4257045	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as inhibition of active Rho protein	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
10.	ALA4257046	B	Inhibition of CNKSR1 in human NSCLC cells expressing wild type KRAS assessed as inhibition of active Rho protein at 10 uM incubated for 2 to 48 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
11.	ALA4257047	B	Inhibition of CNKSR1 in human NSCLC cells expressing wild type KRAS assessed as inhibition of active RalB protein at 10 uM incubated for 2 to 48 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
12.	ALA4257048	B	Inhibition of CNKSR1 in human NSCLC cells expressing wild type KRAS assessed as inhibition of active RalA protein at 10 uM incubated for 2 to 48 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
13.	ALA4257049	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in ERK phosphorylation at 1 to 20 uM incubated for 24 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
14.	ALA4257050	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in EGFR phosphorylation at 1 to 20 uM incubated for 24 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
15.	ALA4257051	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in ERK phosphorylation at 3 to 30 uM incubated for 24 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
16.	ALA4257052	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in EGFR phosphorylation at 3 to 10 uM incubated for 24 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
17.	ALA4257053	B	Inhibition of CNKSR1 in human NCI-H1573 cells expressing mutant KRAS assessed as reduction in EGFR phosphorylation at 30 uM incubated for 24 hrs	Homo sapiens	1	ALA4257006	cell-based format	Patent Bioactivity Data
18.	ALA4257055	B	Competitive inhibition of CNK1 (unknown origin) binding to PIP3 (unknown origin) by SPR spectroscopy	Homo sapiens	3	ALA4257006	assay format	Patent Bioactivity Data
19.	ALA4419254	B	Binding affinity to CNKSR1 PH-domain (unknown origin) by SPR spectroscopy	Homo sapiens	46	ALA4419164	single protein format	Patent Bioactivity Data
20.	ALA4419265	B	Inhibition of CNKSR1 PH-domain (unknown origin) assessed as reduction in c-RAF Ser338 phosphorylation at 25 to 50 uM by cell based Western blot analysis	Homo sapiens	1	ALA4419164	cell-based format	Patent Bioactivity Data