# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4201169 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells or HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 1 | ALA4196177 | cell-based format | Scientific Literature | |
2. | ALA4201183 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | ALA4196177 | cell-based format | Scientific Literature | |
3. | ALA4201184 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced intracellular protein aggregation expressed in human HeLa cells at 0.4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | ALA4196177 | cell-based format | Scientific Literature | |
4. | ALA4201185 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced intracellular protein aggregation expressed in human HLE-B3 cells at 4 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | ALA4196177 | cell-based format | Scientific Literature | |
5. | ALA4201186 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced intracellular protein aggregation expressed in human HLE-B3 cells at 0.44 uM incubated for 6 to 8 hrs by fluorescence microscopy relative to untreated control | Homo sapiens | 6 | ALA4196177 | cell-based format | Scientific Literature | |
6. | ALA4201196 | B | Induction of redissolving of aggregated gamma-crystallin D W43R mutant (unknown origin) at 200 uM incubated for 24 hrs by ThT-fluorescence based assay | Homo sapiens | 2 | ALA4196177 | single protein format | Scientific Literature | |
7. | ALA4201205 | B | Induction of redissolving of aggregated gamma-crystallin D W43R mutant (unknown origin) at 200 uM incubated for 24 hrs by transmission-electron-microscopy | Homo sapiens | 2 | ALA4196177 | single protein format | Scientific Literature | |
8. | ALA4201219 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced cytotoxicity in human HeLa cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay | Homo sapiens | 5 | ALA4196177 | cell-based format | Scientific Literature | |
9. | ALA4201220 | B | Inhibition of gamma-crystallin D W43R mutant (unknown origin)-induced cytotoxicity in human HLE-B3 cells assessed as increase in cell viability at 0.04 to 4 uM incubated for 12 hrs by CCK8 assay | Homo sapiens | 5 | ALA4196177 | cell-based format | Scientific Literature |