# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4257032 | F | Growth inhibition of human NCI-H1373 cells expressing mutant KRAS incubated for 72 hrs by MTS assay | Homo sapiens | 18 | cell-based format | Patent Bioactivity Data | ||
2. | ALA4419258 | F | Growth inhibition of human NCI-H1373 cells relative to control | Homo sapiens | 2 | cell-based format | Patent Bioactivity Data | ||
3. | ALA4419288 | F | Growth inhibition of human NCI-H1373 cells incubated for 3 days | Homo sapiens | 31 | cell-based format | Patent Bioactivity Data | ||
4. | ALA4828609 | F | Cytotoxicity against human NCI-H1373 cells harboring KRAS G12C mutant assessed as reduction in cell viability measured after 72 hrs by CellTiter-Glo luciferase-based ATP detection assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA4828614 | F | Cytotoxicity against human NCI-H1373 cells harboring KRASG12C mutant assessed as reduction in cell viability measured after 72 hrs in presence of compound 1 by CellTiter-Glo luciferase-based ATP detection assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
6. | ALA4886595 | F | H1373 cell line Proliferation assay | Homo sapiens | 1 | cell-based format | Donated Chemical Probes - SGC Frankfurt | ||
7. | ALA5109545 | F | Growth inhibition of human NCI-H1373 cells assessed as cell viability after 6 days by CellTiter-Glo assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
8. | ALA5109556 | F | Antitumor activity against human NCI-H1373 cells xenografted in nude mouse assessed as inhibition of p-ERK levels at 33 mg/kg, sc administered as single dose and measured after 6 hrs | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
9. | ALA5109557 | F | Antitumor activity against human NCI-H1373 cells xenografted in nude mouse assessed as tumor growth inhibition at 3 mg/kg, sc administered as single dose | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
10. | ALA5109558 | F | Antitumor activity against human NCI-H1373 cells xenografted in nude mouse assessed as tumor growth inhibition at 10 mg/kg, sc administered as single dose | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
11. | ALA5109559 | F | Antitumor activity against human NCI-H1373 cells xenografted in nude mouse assessed as tumor growth inhibition at 30 mg/kg, sc administered as single dose | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
12. | ALA5124508 | F | Antitumor activity against human NCI-H1373 cells in xenograft model assessed as tumor growth inhibition relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA5150145 | F | Antiproliferative activity against human NCI-H1373 cells harboring KRAS G12D mutant measured after 24 hrs by CellTiterGlo assay | Homo sapiens | 1 | cell-based format | Scientific Literature |