# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1913171 | Functional | Inhibition of VEGF-induced angiogenesis in C57BL/6 mouse aortic rings assessed as decrease in microvessel sprouting after 7 days | Mus musculus | 1 | ALA1909624 | tissue-based format | Scientific Literature | |
2. | ALA3997741 | Toxicity | Toxicity in mouse isolated aorta assessed as effect on contractility | Mus musculus | 1 | ALA3994677 | tissue-based format | Scientific Literature | |
3. | ALA4183451 | Functional | Antiangiogenic activity in wild type C57Bl/6 mouse aortic ring assessed as inhibition of VEGFA-induced vessel sprouting at 30 uM after 7 days relative to control | Mus musculus | 1 | ALA4177756 | tissue-based format | Scientific Literature | |
4. | ALA4257265 | Functional | Inhibition of sprouting in mouse aorta cultured in collagen gels at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
5. | ALA4257266 | Functional | Inhibition of branching in mouse aorta cultured in collagen gels assessed as reduction in number of branch-points at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
6. | ALA4257272 | Functional | Inhibition of endothelial cell migration in VEGF165-stimulated C57BL16 mouse aortic rings incubated in collagen matrix assessed as induction of shorter sprouts incubated for 10 days by aortic ring assay | Mus musculus | 3 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
7. | ALA4257273 | Functional | Inhibition of endothelial cell migration in VEGF165-stimulated C57BL16 mouse aortic rings incubated in collagen matrix assessed as reduction in microvascular density incubated for 10 days by aortic ring assay | Mus musculus | 3 | ALA4257222 | tissue-based format | Patent Bioactivity Data | |
8. | ALA4422523 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as reduction in aortic ring sprouting at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
9. | ALA4422524 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as reduction in initial sprouting at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
10. | ALA4422525 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta cultured in collagen gels assessed as attenuation of branching at 7.5 uM by aortic ring sprouting assay | Mus musculus | 7 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
11. | ALA4422531 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta assessed as reduction in sprout shortening using compound applied from first day of culture over a 10-day period with medium change every two days | Mus musculus | 3 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
12. | ALA4422532 | Functional | Inhibition of micro-vessel branching in C57BL16 mouse aorta assessed as reduction in microvascular density using compound applied from first day of culture over a 10-day period with medium change every two days | Mus musculus | 3 | ALA4421732 | tissue-based format | Patent Bioactivity Data | |
13. | ALA4476898 | Functional | Inhibition of vascular sprouting in CD36+/+ C57BL/6 mouse aortic rings exposed on day 4 to 6 | Mus musculus | 1 | ALA4476864 | tissue-based format | Patent Bioactivity Data | |
14. | ALA4476899 | Functional | Inhibition of vascular sprouting in CD36-/- C57BL/6 mouse aortic rings exposed on day 4 to 6 | Mus musculus | 1 | ALA4476864 | tissue-based format | Patent Bioactivity Data |