| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1118230 | F | Antagonist activity at human TRPV4 channel | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA1176321 | F | Antagonist activity at human TRPV4 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA1224915 | F | Agonist activity at TRPV4 | 2 | assay format | Scientific Literature | |||
| 4. | ALA1252948 | B | Activation of TRPV4 in HEK cells assessed as increase in Ca2+ level from extracellular space at 300 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1252949 | B | Activation of TRPV4 in HEK cells assessed as increase in Ca2+ level from extracellular space at 10 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1292430 | B | Inhibition of TRPV4 receptor up to 10 uM | 1 | single protein format | Scientific Literature | |||
| 7. | ALA1816279 | B | Inhibition of human TRPV4 by fluorescent-based live-cell assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA1820168 | F | Agonist activity at human TRPV4 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA1820169 | F | Antagonist activity at human TRPV4 receptor | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA2327056 | B | Agonist activity at human TRPV4 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA2327222 | B | Antagonist activity at human recombinant TRPV4 expressed in BacMam virus infected HEK MSRII cells assessed as inhibition of GSK1016790A-induced calcium immobilization treated 10 mins prior to TRPV4 agonist, GSK1016790A by FLIPR assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 12. | ALA2327244 | B | Antagonist activity at TRPV4 (unknown origin) by ligand-gated assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA2328089 | B | Inhibition of TRPV4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA2328090 | B | Agonist activity at TRPV4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA2422132 | B | Inhibition of TRPV4 (unknown origin) by FLIPR assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA2444597 | B | Antagonist activity at human TRPV4 expressed in CHO cells assessed as inhibition of 4alphaPDD-induced 45Ca2+ uptake at 1 uM incubated for 10 mins prior to 4alphaPDD-challenge measured after 2 to 5 mins by liquid scintillation counting analysis | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 17. | ALA3227111 | B | Antagonist activity at human TRPV4 | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 18. | ALA3227452 | B | Agonist activity at human TRPV4 expressed in CHOK1 cells assessed as changes in intracellular calcium level measured for 5 mins by FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA3227453 | B | Antagonist activity at human TRPV4 expressed in CHOK1 cells assessed as inhibition of PF-04674114/GSK1016790A-induced changes in intracellular calcium level measured for 5 mins by FLIPR assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 20. | ALA3383309 | B | Antagonist activity at human TRPV4 expressed in HEK293 cells assessed as inhibition of hypotonic solution-induced Ca2+ influx | Homo sapiens | 1 | cell-based format | Scientific Literature |
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