| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2343867 | F | Inhibition of intracellular A2E photooxidation in human ARPE19 cells at 20 uM after 18 days | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 2. | ALA5255945 | T | Cytotoxicity against human ARPE-19 cells assessed as cell growth inhibition incubated for 44 hrs by AlamarBlue reagent based fluorescence assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA5252414 | F | Cytoprotective activity in human ARPE-19 cells assessed as cell viability at 25 uM preincubated for 4 hrs followed by palmitate addition and measured after 24 hrs by cello-meter auto T4 bright field cell counter method | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA5252423 | F | Cytoprotective activity in human ARPE-19 cells assessed as decrease in VEGF secretion at 25 uM preincubated for 4 hrs followed by cobalt chloride addition measured by ELISA method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA5252424 | F | Cytoprotective activity in human ARPE-19 cells assessed as reduction in production of reactive oxygen species at 25 uM preincubated with compound for 4 hrs followed by palmitate addition and measured after 24 hrs by microplate reader analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3742780 | F | Neuroprotective activity against Fenton reagent-induced ROS generation in human ARPE19 cells assessed as increase in GSH level at 1 mM after 2 hrs by DTNB method | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 7. | ALA4058198 | F | Cytoprotective activity against H2O2-induced toxicity in human ARPE19 cells up to 100 uM pretreated for 5 hrs followed by H2O2 addition after 19 hrs by CellTiter-blue assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4058199 | F | Cytoprotective activity against H2O2-induced toxicity in human ARPE19 cells pretreated for 5 hrs followed by H2O2 addition after 19 hrs by CellTiter-blue assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 9. | ALA4058200 | A | Cytotoxicity against human ARPE19 cells assessed as reduction in cell viability up to 100 uM after 72 hrs by CellTiter-blue assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 10. | ALA4058228 | A | Cytotoxicity against human ARPE19 cells assessed as reduction in cell viability at 100 uM after 72 hrs by CellTiter-blue assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4182652 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as viable cells level at 5 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 59.1%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4182653 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as early apoptosis cells level at 5 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 17.6%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4182654 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as late apoptosis cells level at 5 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 23%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4182655 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as necrosis cells level at 5 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 0.342%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4182656 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as viable cells level at 10 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 59.1%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4182657 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as early apoptosis cells level at 10 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 17.6%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4182658 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as late apoptosis cells level at 10 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 23%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4182659 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as necrosis cells level at 10 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 0.342%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4182660 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as viable cells level at 20 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 59.1%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4182661 | F | Suppression of 4-HNE-induced apoptosis in human ARPE19 cells assessed as early apoptosis cells level at 20 uM incubated for 24 hrs by FITC Annexin V and propidium iodide staining based flow cytometry (Rvb = 17.6%) | Homo sapiens | 2 | cell-based format | Scientific Literature |
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