| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2341490 | F | Induction of DNA damage in human BT-483 cells assessed as gamma H2AX phosphorylation at Ser139 at 1 to 10 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA2341491 | F | Induction of DNA damage in human BT-483 cells assessed as gamma H2AX phosphorylation at Ser139 at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA2341492 | F | Induction of apoptosis in human BT-483 cells assessed as PARP cleavage at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA2341493 | F | Induction of apoptosis in human BT-483 cells assessed as increase in caspase 3 activity at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4254241 | F | Cytotoxicity against human BT-483 cells after 24 hrs by MTT assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 6. | ALA4254242 | F | Induction of apoptosis in human BT-483 cells assessed as apoptotic nuclear fragment formation at 5 uM after 24 hrs by fluorescence microscopic method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4254243 | F | Induction of apoptosis in human BT-483 cells assessed as live cells at 5 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 87.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4254244 | F | Induction of apoptosis in human BT-483 cells assessed as early apoptotic cells at 5 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 2.01%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4254245 | F | Induction of apoptosis in human BT-483 cells assessed as late apoptotic cells at 5 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.36%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4254246 | F | Induction of apoptosis in human BT-483 cells assessed as necrotic cells at 5 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.18%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4254247 | F | Induction of apoptosis in human BT-483 cells assessed as live cells at 10 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 87.5%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4254248 | F | Induction of apoptosis in human BT-483 cells assessed as early apoptotic cells at 10 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 2.01%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4254249 | F | Induction of apoptosis in human BT-483 cells assessed as late apoptotic cells at 10 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.36%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4254250 | F | Induction of apoptosis in human BT-483 cells assessed as necrotic cells at 10 uM by Annexin V-FITC/propidium iodide staining based flow cytometry (Rvb = 0.18%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4254251 | F | Induction of apoptosis in human BT-483 cells by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4254257 | F | Induction of autophagy in human BT-483 cells transfected with GFP-fused LC3 assessed as aggregation of GFP-LC3 punctures after 6 hrs by DAPI staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4254258 | F | Cell cycle arrest in human BT-483 cells assessed as accumulation at sub-G1 phase at 5 to 10 uM after 24 to 72 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4254259 | F | Cell cycle arrest in human BT-483 cells assessed as accumulation at G2/M phase at 5 to 10 uM after 24 to 72 hrs | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4254262 | A | Effect on total PLK1 protein expression in human BT-483 cells at 5 to 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4254263 | A | Effect on total EEF2K protein expression in human BT-483 cells at 5 to 10 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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