# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA990721 | F | Induction of apoptosis in human CNE2 cells assessed as DNA fragmentation at 50 uM after 24 hrs by agarose gel electrophoresis | Homo sapiens | 4 | ALA1151690 | cell-based format | Scientific Literature | |
2. | ALA990723 | F | Induction of apoptosis in human CNE2 cells assessed as early stage apoptotic cell count at 5 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
3. | ALA990724 | F | Induction of apoptosis in human CNE2 cells assessed as early stage apoptotic cell count at 10 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
4. | ALA990725 | F | Induction of apoptosis in human CNE2 cells assessed as early stage apoptotic cell count at 25 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
5. | ALA990726 | F | Induction of apoptosis in human CNE2 cells assessed as early stage apoptotic cell count at 50 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
6. | ALA990727 | F | Induction of apoptosis in human CNE2 cells assessed as late stage apoptotic cell count at 5 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
7. | ALA990728 | F | Induction of apoptosis in human CNE2 cells assessed as late stage apoptotic cell count at 10 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
8. | ALA990729 | F | Induction of apoptosis in human CNE2 cells assessed as late stage apoptotic cell count at 25 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
9. | ALA990730 | F | Induction of apoptosis in human CNE2 cells assessed as late stage apoptotic cell count at 50 uM after 24 hrs by Annexin-V-FITC/PI binding assay | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
10. | ALA990731 | F | Induction of apoptosis in human CNE2 cells assessed as caspase 3-mediated PARP cleavage at 50 uM after 24 hrs by enhanced chemiluminescence detection | Homo sapiens | 4 | ALA1151690 | cell-based format | Scientific Literature | |
11. | ALA990732 | F | Induction of apoptosis in human CNE2 cells assessed as increase in caspase 9 activity at 50 uM upto 24 hrs | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
12. | ALA990733 | F | Induction of apoptosis in human CNE2 cells assessed as intracellular ROS production visualized by DCFH-DA after 30 hrs by FACS analysis | Homo sapiens | 1 | ALA1151690 | cell-based format | Scientific Literature | |
13. | ALA4051091 | F | Phototoxicity in human CNE2 cells assessed as reduction in cell viability preincubated for 4 hrs followed by irradiation with 6 J/cm2 light dose measured after 24 hrs by MTT assay | Homo sapiens | 1 | ALA4049424 | cell-based format | Scientific Literature | |
14. | ALA4051092 | F | Phototoxicity in human CNE2 cells assessed as reduction in cell viability preincubated for 4 hrs followed by irradiation with 4 J/cm2 light dose measured after 24 hrs by MTT assay | Homo sapiens | 1 | ALA4049424 | cell-based format | Scientific Literature | |
15. | ALA4051093 | F | Potency index, ratio of ALA LD80 to test compound LD80 for phototoxicity against human CNE2 cells | Homo sapiens | 1 | ALA4049424 | cell-based format | Scientific Literature | |
16. | ALA4119315 | F | Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 3 days by MTT assay | Homo sapiens | 4 | ALA4118045 | cell-based format | Scientific Literature | |
17. | ALA4136757 | F | Antiproliferative activity against human CNE2 cells after 48 hrs by MTT assay | Homo sapiens | 10 | ALA4130604 | cell-based format | Scientific Literature | |
18. | ALA4156635 | F | Cytotoxicity against human CNE2 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 32 | ALA4152337 | cell-based format | Scientific Literature | |
19. | ALA4187907 | F | Anticancer activity against human CNE2 cells assessed as reduction in cell viability incubated for 48 hrs MTT assay | Homo sapiens | 59 | ALA4184236 | cell-based format | Scientific Literature | |
20. | ALA4187908 | F | Induction of apoptosis in human CNE2 cells assessed as viable cells level at 5 uM incubated for 24 hrs by Annexin V-FITC/PI dual staining based flow cytometry (Rvb = 91.6%) | Homo sapiens | 1 | ALA4184236 | cell-based format | Scientific Literature |