| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4259990 | F | Cytoprotection against DEM-induced toxicity in human GM16216 cells assessed as increase in cell viability at 0.1 to 2.5 uM pretreated for 16 hrs followed by DEM addition and measured after 5 hrs by live/dead staining based flow cytometry | Homo sapiens | 1 | ALA4257548 | cell-based format | Scientific Literature | |
| 2. | ALA4259992 | F | Cytoprotection against DEM-induced toxicity in human GM16216 cells assessed as increase in cell viability pretreated for 16 hrs followed by DEM addition and measured after 5 hrs by live/dead staining based flow cytometry | Homo sapiens | 3 | ALA4257548 | cell-based format | Scientific Literature | |
| 3. | ALA4259994 | F | Cytoprotection against DEM-induced toxicity in human GM16216 cells assessed as increase in cell viability at 0.5 to 2.5 uM pretreated for 16 hrs followed by DEM addition and measured after 5 hrs by live/dead staining based flow cytometry | Homo sapiens | 4 | ALA4257548 | cell-based format | Scientific Literature | |
| 4. | ALA4259996 | F | Effect on mitochondrial membrane potential in human GM16216 cells assessed as loss of mitochondrial membrane potential at 2.5 uM after 16 hrs by JC1 staining based flow cytometry (Rvb = 13%) | Homo sapiens | 11 | ALA4257548 | cell-based format | Scientific Literature | |
| 5. | ALA4259997 | F | Effect on mitochondrial membrane potential in human GM16216 cells assessed as intact mitochondrial membrane at 2.5 uM after 16 hrs by JC1 staining based flow cytometry (Rvb = 87%) | Homo sapiens | 11 | ALA4257548 | cell-based format | Scientific Literature | |
| 6. | ALA4259998 | F | Effect on mitochondrial membrane potential in human GM16216 cells assessed as loss of mitochondrial membrane potential at 0.25 uM after 16 hrs by JC1 staining based flow cytometry (Rvb = 13%) | Homo sapiens | 10 | ALA4257548 | cell-based format | Scientific Literature | |
| 7. | ALA4259999 | F | Effect on mitochondrial membrane potential in human GM16216 cells assessed as intact mitochondrial membrane at 0.25 uM after 16 hrs by JC1 staining based flow cytometry (Rvb = 87%) | Homo sapiens | 10 | ALA4257548 | cell-based format | Scientific Literature | |
| 8. | ALA4260005 | A | Cytotoxicity against human GM16216 cells at 2.5 uM after 24 to 48 hrs by live/dead staining-based flow cytometry | Homo sapiens | 3 | ALA4257548 | cell-based format | Scientific Literature | |
| 9. | ALA4260007 | A | Cytotoxicity against human GM16216 cells at 0.25 to 2.5 uM after 24 to 48 hrs by live/dead staining-based flow cytometry | Homo sapiens | 4 | ALA4257548 | cell-based format | Scientific Literature | |
| 10. | ALA4260009 | A | Cytotoxicity against human GM16216 cells at 2.5 uM after 48 hrs by live/dead staining-based flow cytometry | Homo sapiens | 1 | ALA4257548 | cell-based format | Scientific Literature | |
| 11. | ALA4260011 | F | Inhibition of ATP production in human GM16216 cells after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 5 | ALA4257548 | cell-based format | Scientific Literature | |
| 12. | ALA4260013 | F | Effect on ATP production in human GM16216 cells at 0.1 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 5 | ALA4257548 | cell-based format | Scientific Literature | |
| 13. | ALA4260015 | F | Increase in ATP production in human GM16216 cells at 0.1 to 0.5 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 2 | ALA4257548 | cell-based format | Scientific Literature | |
| 14. | ALA4260017 | F | Inhibition of ATP production in human GM16216 cells at 2.5 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 4 | ALA4257548 | cell-based format | Scientific Literature | |
| 15. | ALA4260019 | F | Increase in ATP production in human GM16216 cells at 0.1 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 1 | ALA4257548 | cell-based format | Scientific Literature | |
| 16. | ALA4260021 | F | Effect on ATP production in human GM16216 cells at 0.5 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 1 | ALA4257548 | cell-based format | Scientific Literature | |
| 17. | ALA4260023 | F | Effect on ATP production in human GM16216 cells at 0.1 to 0.5 uM after 24 hrs by Vialight reagent based luminescence assay | Homo sapiens | 1 | ALA4257548 | cell-based format | Scientific Literature | |
| 18. | ALA4260025 | F | Increase in frataxin expression in human GM16216 cells at 50 to 250 nM after 24 to 48 hrs by ELISA | Homo sapiens | 4 | ALA4257548 | cell-based format | Scientific Literature | |
| 19. | ALA4260027 | F | Induction of mitochondrial biogenesis in human GM16216 cells assessed as increase in ratio of COX1 to SDH-A protein levels at 50 to 250 nM after 24 to 48 hrs by ELISA | Homo sapiens | 4 | ALA4257548 | cell-based format | Scientific Literature | |
| 20. | ALA4260029 | F | Increase in frataxin expression in human GM16216 cells at 50 nM after 24 to 48 hrs by ELISA | Homo sapiens | 2 | ALA4257548 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!