| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2034029 | F | Induction of apoptosis in human HCC827 cells harboring EGFR del E746-A750 mutant after 72 hrs by flow cytometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA2034031 | F | Induction of Cell cycle arrest in human HCC827 cells harboring EGFR del E746-A750 mutant assessed as G1 phase cells after 24 hrs by flow cytometry assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA1058059 | F | Induction of mutant EGFR degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1058060 | F | Induction of mutant Met degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1058061 | F | Induction of mutant p-Akt degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1058062 | F | Induction of mutant c-Raf degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1058063 | F | Induction of mutant Cyclin D degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1058064 | F | Induction of mutant Cdk4 degradation in human tarceva and iressa-resistant HCC827 cells at 20 to 500 nM by Western blotting | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2383964 | F | Induction of apoptosis in gefitinib-sensitive human HCC827 cells harboring EGFR E746_A740 deletion mutant after 24 hrs by annexin-V/7-AAD staining-based FACS flow cytometric analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3267444 | F | Induction of apoptosis in human HCC827 cells at 1 uM after 24 hrs using propidium iodide by flow cytometry | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3997312 | F | Cytotoxicity against human erlotinib-resistant HCC827 cells assessed as growth inhibition after 48 hrs by CCK8 assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 12. | ALA3999843 | F | Antiproliferative activity against human HCC827 cells harboring EGFR E746_A750 deletion mutant after 48 hrs by MTT assay | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 13. | ALA4004419 | F | Antiproliferative activity against human HCC827 cells using 1% DMSO/water compound formulation after 72 hrs by MTT assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4004420 | F | Antiproliferative activity against human HCC827 cells using 10% 2-HPbetaCD compound formulation after 72 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4025989 | F | Antiproliferative activity against human HCC827 cells harboring EGFR del E746 to A750 mutant assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 16. | ALA4041202 | F | Antiproliferative activity against gefitinib resistant EGFR-mutated human HCC827 cells after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4041203 | F | Induction of apoptosis in gefitinib resistant human HCC827 cells at 0.1 uM after 72 hrs by annexin V-FITC-propidium iodide staining-based flow cytometry method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4041204 | F | Induction of apoptosis in gefitinib resistant human HCC827 cells at 0.5 uM after 72 hrs by annexin V-FITC-propidium iodide staining-based flow cytometry method relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4041209 | F | Antitumor activity against gefitinib resistant human HCC827 cells xenografted in balb/c athymic nu/nu mouse assessed as decrease in tumor size at 15 mg/kg/day, po | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA4041211 | F | Downregulation of SMO expression in gefitinib resistant human HCC827 cells at 0.05 to 0.1 uM after 72 hrs by Western blotting method | Homo sapiens | 1 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!