| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1112527 | F | Inhibition of FCepsilonRI expression in human HMC1 cells at 100 uM after 72 hrs by flow cytometry | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 2. | ALA1112528 | F | Inhibition of FCepsilonRI expression in human HMC1 cells at 50 to 100 uM after 72 hrs by flow cytometry | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 3. | ALA1112529 | F | Inhibition of FCepsilonRI gamma subunit mRNA expression in human HMC1 cells at 50 uM after 36 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA1112530 | F | Inhibition of FCepsilonRI alpha subunit mRNA expression in human HMC1 cells at 50 uM after 36 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1112531 | F | Inhibition of FCepsilonRI beta subunit mRNA expression in human HMC1 cells at 50 uM after 36 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1694147 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated IL-6 secretion by ELISA method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA1694265 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated IL-6 mRNA expression at 1 to 100 uM treated 1 hr prior to 5 hrs phorbol 12-myristate 13-acetate/A23187 challenge by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA1694266 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated histamine secretion at 100 uM treated 1 hr prior to 6 hrs phorbol 12-myristate 13-acetate/A23187 challenge by histamine assay kit | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA1694268 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated p38 phosphorylation at 1 to 100 uM treated 1 hr prior to 30 mic phorbol 12-myristate 13-acetate/A23187 challenge | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA1694269 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated JNK phosphorylation at 1 to 100 uM treated 1 hr prior to 30 mic phorbol 12-myristate 13-acetate/A23187 challenge | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA1694270 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated ERK phosphorylation at 1 to 100 uM treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA1694274 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated RIP-2 activation at 1 to 100 uM treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA1694275 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated caspase 1 activation at 1 to 100 uM treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA1694276 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated caspase 1 activation at 1 to 100 uM treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge by caspase colorimetric assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA1694277 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated IL1-beta secretion at 1 to 100 uM treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA1694278 | F | Immunomodulatory activity in human HMC1 cells assessed as inhibition of phorbol 12-myristate 13-acetate/A23187-stimulated IL1-beta secretion treated 1 hr prior to 30 mins phorbol 12-myristate 13-acetate/A23187 challenge by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA3372490 | F | Inhibition of A23187-induced IL-6 production in human HMC1 cells incubated for 30 mins prior to A23187 challenge measured after 24 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4038504 | A | Cytotoxicity against HMC1 cells assessed as reduction in cell viability at 1.8 to 30 uM after 24 hrs by trypan blue assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4222054 | F | Antiinflammatory activity in human HMC1 cells assessed as reduction in PMA/ionophore A23187-induced TNFalpha mRNA expression at 0.8 to 20 uM pretreated for 30 mins followed by PMA/ionophore challenge measured after 24 hrs by real-time PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4222055 | F | Antiinflammatory activity in human HMC1 cells assessed as reduction in PMA/ionophore A23187-induced IL-6 production | Homo sapiens | 2 | cell-based format | Scientific Literature |
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