# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA920581 | F | Reduction of TNFalpha mRNA level in cystic fibrosis IB3-1 cells at 8 ug after 24 hrs relative to control | Homo sapiens | 1 | ALA1142091 | cell-based format | Scientific Literature | |
2. | ALA920584 | F | Reduction of TNFalpha protein level in cystic fibrosis IB3-1 cells at 8 ug after 24 hrs by ELISA relative to control | Homo sapiens | 1 | ALA1142091 | cell-based format | Scientific Literature | |
3. | ALA920587 | F | Reduction of NF-kappaB binding to DNA in cystic fibrosis IB3-1 cells at 8 ug after 24 hrs | Homo sapiens | 2 | ALA1142091 | cell-based format | Scientific Literature | |
4. | ALA920590 | F | Reduction of Sp1 binding to DNA in cystic fibrosis IB3-1 cells at 8 ug after 24 hrs | Homo sapiens | 2 | ALA1142091 | cell-based format | Scientific Literature | |
5. | ALA4152777 | A | Antiproliferative activity against human IB3-1 cells after 2 days by cell counting analysis | Homo sapiens | 7 | ALA4152196 | cell-based format | Scientific Literature | |
6. | ALA4152823 | F | Inhibition of TNF-alpha induced PDGF-B chain production in human IB3-1 cells at 1 uM preincubated for 5 hrs followed by TNF-alpha stimulation and measured after 24 hrs relative to control | Homo sapiens | 1 | ALA4152196 | cell-based format | Scientific Literature | |
7. | ALA4152824 | F | Inhibition of TNF-alpha induced IL-10 production in human IB3-1 cells at 1 uM preincubated for 5 hrs followed by TNF-alpha stimulation and measured after 24 hrs relative to control | Homo sapiens | 1 | ALA4152196 | cell-based format | Scientific Literature | |
8. | ALA4152825 | F | Inhibition of TNF-alpha induced IL-15 production in human IB3-1 cells at 1 uM preincubated for 5 hrs followed by TNF-alpha stimulation and measured after 24 hrs relative to control | Homo sapiens | 1 | ALA4152196 | cell-based format | Scientific Literature | |
9. | ALA4152826 | F | Inhibition of TNF-alpha induced IL-17 production in human IB3-1 cells at 1 uM preincubated for 5 hrs followed by TNF-alpha stimulation and measured after 24 hrs relative to control | Homo sapiens | 1 | ALA4152196 | cell-based format | Scientific Literature | |
10. | ALA4152827 | F | Inhibition of TNF-alpha induced IFN-gamma production in human IB3-1 cells at 1 uM preincubated for 5 hrs followed by TNF-alpha stimulation and measured after 24 hrs relative to control | Homo sapiens | 1 | ALA4152196 | cell-based format | Scientific Literature | |
11. | ALA4407716 | F | Antiproliferative activity against human IB31 cells after 2 days | Homo sapiens | 8 | ALA4406814 | cell-based format | Scientific Literature |