# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4418624 | ADME | Growth inhibition of rat IEC-6 cells | Rattus norvegicus | 1 | ALA4418485 | cell-based format | Patent Bioactivity Data | |
2. | ALA4418634 | ADME | Growth inhibition of rat IEC-6 cells relative to control | Rattus norvegicus | 1 | ALA4418485 | cell-based format | Patent Bioactivity Data | |
3. | ALA4124678 | ADME | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability after 3 days by CellTiter-Glo assay | Rattus norvegicus | 2 | ALA4118248 | cell-based format | Scientific Literature | |
4. | ALA4192853 | ADME | Cytotoxicity against rat IEC-6 cells assessed as survival rate at 10 uM after 48 hrs by MTT assay relative to control | Rattus norvegicus | 1 | ALA4190281 | cell-based format | Scientific Literature | |
5. | ALA4223971 | ADME | Cytotoxicity against rat IEC-6 cells assessed as cell survival at 10 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 29 | ALA4219240 | cell-based format | Scientific Literature | |
6. | ALA4323949 | ADME | Cytotoxicity against rat IEC-6 cells assessed as cell viability after 72 hrs by MTT assay | Rattus norvegicus | 1 | ALA4321837 | cell-based format | Scientific Literature | |
7. | ALA4329126 | Functional | Inhibition of apoptosis in rat IEC-6 cells assessed as decrease in CPT-induced DNA fragmentation relative to control | Rattus norvegicus | 2 | ALA4325894 | cell-based format | Scientific Literature | |
8. | ALA4329127 | Functional | Inhibition of apoptosis in rat IEC-6 cells assessed as decrease in CPT-induced DNA fragmentation | Rattus norvegicus | 1 | ALA4325894 | cell-based format | Scientific Literature | |
9. | ALA4340718 | ADME | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability measured after 24 to 72 hrs by MTT assay | Rattus norvegicus | 5 | ALA4340507 | cell-based format | Scientific Literature | |
10. | ALA4340719 | ADME | Cell cycle arrest in rat IEC-6 cells assessed as accumulation at G0/G1-phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
11. | ALA4340760 | ADME | Induction of apoptosis in rat IEC-6 cells assessed as increase in hypodiploid nuclei at 0.1 to 0.6 uM measured after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
12. | ALA4340761 | ADME | Cell cycle arrest in rat IEC-6 cells assessed as increase in accumulation at S phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining based FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
13. | ALA4340764 | ADME | Cell cycle arrest in rat IEC-6 cells assessed as decrease in accumulation at G2-phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
14. | ALA4340766 | ADME | Induction of ROS generation in rat IEC-6 cells at 0.1 to 0.6 uM measured after 24 hrs by H2DCF-DA staining-based FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
15. | ALA4340768 | ADME | Induction of apoptosis in rat IEC-6 cells assessed as increase in caspase 3 level at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
16. | ALA4340770 | ADME | Down regulation of ERK expression in rat IEC-6 cells at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 1 | ALA4340507 | cell-based format | Scientific Literature | |
17. | ALA4340774 | ADME | Induction of apoptosis in rat IEC-6 cells assessed as effect on PARP level at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 2 | ALA4340507 | cell-based format | Scientific Literature | |
18. | ALA4340776 | ADME | Down regulation of ERK expression in rat IEC-6 cells at 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 1 | ALA4340507 | cell-based format | Scientific Literature | |
19. | ALA4340780 | ADME | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability at 0.1 to 0.6 uM measured after 24 to 72 hrs by MTT assay | Rattus norvegicus | 1 | ALA4340507 | cell-based format | Scientific Literature | |
20. | ALA4477589 | ADME | Cytotoxicity against rat IEC-6 cells assessed as survival at 10 uM by MTT assay | Rattus norvegicus | 15 | ALA4477180 | cell-based format | Scientific Literature |