# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4124678 | A | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability after 3 days by CellTiter-Glo assay | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
2. | ALA4192853 | A | Cytotoxicity against rat IEC-6 cells assessed as survival rate at 10 uM after 48 hrs by MTT assay relative to control | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
3. | ALA4223971 | A | Cytotoxicity against rat IEC-6 cells assessed as cell survival at 10 uM after 72 hrs by MTT assay relative to control | Rattus norvegicus | 29 | cell-based format | Scientific Literature | ||
4. | ALA4323949 | A | Cytotoxicity against rat IEC-6 cells assessed as cell viability after 72 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
5. | ALA4329126 | F | Inhibition of apoptosis in rat IEC-6 cells assessed as decrease in CPT-induced DNA fragmentation relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA4329127 | F | Inhibition of apoptosis in rat IEC-6 cells assessed as decrease in CPT-induced DNA fragmentation | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
7. | ALA4340718 | A | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability measured after 24 to 72 hrs by MTT assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
8. | ALA4340719 | A | Cell cycle arrest in rat IEC-6 cells assessed as accumulation at G0/G1-phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
9. | ALA4340760 | A | Induction of apoptosis in rat IEC-6 cells assessed as increase in hypodiploid nuclei at 0.1 to 0.6 uM measured after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
10. | ALA4340761 | A | Cell cycle arrest in rat IEC-6 cells assessed as increase in accumulation at S phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining based FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
11. | ALA4340764 | A | Cell cycle arrest in rat IEC-6 cells assessed as decrease in accumulation at G2-phase at 0.1 to 0.6 uM after 24 hrs by propidium iodide staining-based FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA4340766 | A | Induction of ROS generation in rat IEC-6 cells at 0.1 to 0.6 uM measured after 24 hrs by H2DCF-DA staining-based FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
13. | ALA4340768 | A | Induction of apoptosis in rat IEC-6 cells assessed as increase in caspase 3 level at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
14. | ALA4340770 | A | Down regulation of ERK expression in rat IEC-6 cells at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
15. | ALA4340774 | A | Induction of apoptosis in rat IEC-6 cells assessed as effect on PARP level at 0.1 to 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
16. | ALA4340776 | A | Down regulation of ERK expression in rat IEC-6 cells at 0.6 uM after 24 hrs by FACS analysis | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
17. | ALA4340780 | A | Cytotoxicity against rat IEC-6 cells assessed as reduction in cell viability at 0.1 to 0.6 uM measured after 24 to 72 hrs by MTT assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
18. | ALA4418624 | A | Growth inhibition of rat IEC-6 cells | Rattus norvegicus | 1 | cell-based format | Patent Bioactivity Data | ||
19. | ALA4418634 | A | Growth inhibition of rat IEC-6 cells relative to control | Rattus norvegicus | 1 | cell-based format | Patent Bioactivity Data | ||
20. | ALA4477589 | A | Cytotoxicity against rat IEC-6 cells assessed as survival at 10 uM by MTT assay | Rattus norvegicus | 15 | cell-based format | Scientific Literature |