| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4006126 | F | Cytotoxicity against human K562R cells assessed as decrease in cell growth after 72 hrs by resazurin dye-based fluorimetric method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 2. | ALA4039048 | F | Growth inhibition of human K562R cells assessed as cell viability at 10 uM after 48 hrs by trypan blue exclusion assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4121808 | F | Cytotoxicity in imatinib-resistant human K562R cells assessed as reduction cell viability incubated for 48 hrs by XTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA4121813 | F | Induction of apoptosis in imatinib-resistant human K562R cells assessed as induction of caspase-3 cleavage after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4121814 | F | Induction of apoptosis in imatinib-resistant human K562R cells assessed as induction of PARP cleavage after 6 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4121817 | F | Induction of apoptosis in imatinib-resistant human K562R cells assessed as induction of caspase-3 cleavage after 24 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4121818 | F | Induction of apoptosis in imatinib-resistant human K562R cells assessed as induction of PARP cleavage after 24 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4121820 | F | Inhibition of autophagy in imatinib-resistant human K562R cells assessed as reduction in LC3-II accumulation by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4143256 | F | Antiproliferative activity against human K562R cells after 72 hrs by resazurin-based fluorescence assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 10. | ALA4268716 | F | Cytotoxicity against human K562R cells assessed as decrease in cell viability after 24 hrs by XTT assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
| 11. | ALA4268721 | F | Induction of apoptosis in human K562R cells assessed as viable cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 81.13%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 12. | ALA4268722 | F | Induction of apoptosis in human K562R cells assessed as early apoptotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 8.51%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 13. | ALA4268723 | F | Induction of apoptosis in human K562R cells assessed as late apoptotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 9.49%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4268724 | F | Induction of apoptosis in human K562R cells assessed as necrotic cells at 10 uM by Annexin V staining-based flow cytometry (Rvb = 0.87%) | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA4268727 | F | Effect on heme oxygenase 2 mRNA levels in human K562R cells at 10 uM by qRT-PCR method | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4268728 | F | Induction of ROS production in human K562R cells at 10 uM by DCFH-DA dye based spectrofluorometric method | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA4326254 | F | Antiproliferative activity against human K562R cells after 72 hrs by MTS assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA4326281 | F | Potency index, ratio of IC50 for TSA to IC50 for test compound for antiproliferative activity against human K562R cells after 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4326282 | F | Potency index, ratio of IC50 for isoCA4 to IC50 for test compound for antiproliferative activity against human K562R cells after 72 hrs by MTS assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4331385 | F | Antiproliferative activity against human K562R cells after 72 hrs by MTS assay | Homo sapiens | 5 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!