| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4042002 | F | Cytotoxicity against human KCL22 cells assessed as cell viability at 1 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 2. | ALA4042003 | F | Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as cell viability at 1 uM after 48 hrs by MTS assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
| 3. | ALA4042004 | F | Cytotoxicity against human KCL22 cells assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay | Homo sapiens | 62 | cell-based format | Scientific Literature | ||
| 4. | ALA4042005 | F | Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as reduction in cell viability at 1 uM after 48 hrs by MTS assay | Homo sapiens | 62 | cell-based format | Scientific Literature | ||
| 5. | ALA4042006 | F | Cytotoxicity against human KCL22 cells assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA4042007 | F | Cytotoxicity against human KCL22 cells harboring ABL1 T315I mutant assessed as reduction in cell viability after 48 hrs by MTS assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 7. | ALA4135580 | F | Growth inhibition of human KCL22 cells up to 1000 nM after 48 hrs by WST-8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4158936 | F | Cytotoxicity against human KCL22 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4158938 | F | Cytotoxicity against imatinib-resistant human KCL22 cells after 72 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4200768 | F | Antitumor activity against human KCL22 cells xenografted in po dosed nude mouse assessed as tumor growth inhibition administered via gavage after 7 days post implantation measured twice weekly | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4200769 | F | Antitumor activity against human KCL22 cells xenografted in nude mouse assessed as tumor growth level at 30 mg/kg, po bid administered via gavage for 7 days post implantation measured twice weekly relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4200770 | F | Antitumor activity against human KCL22 cells xenografted in nude mouse assessed as tumor growth level at 3 mg/kg, po bid administered via gavage for 7 days post implantation measured twice weekly relative to control | Homo sapiens | 4 | organism-based format | Scientific Literature | ||
| 13. | ALA4200845 | F | Antitumor activity against human KCL22 cells xenografted in po dosed nude mouse assessed as tumor growth inhibition administered as solid dispersion after 7 days post implantation measured twice weekly | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4200846 | F | Antitumor activity against human KCL22 cells xenografted in nude mouse assessed as tumor regression at >=7.5 mg/kg, po bid administered as solid dispersion after 7 days post implantation measured twice weekly | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4266343 | F | Induction of apoptosis in human KCL22 cells by Annexin V staining based assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4387603 | F | Inhibition of cell expansion in human KCL22 cells at 0.3 to 3 uM incubated for 48 hrs by trypan blue dye exclusion counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4387604 | F | Inhibition of cell expansion in human KCL22 cells at 3 uM incubated for 48 hrs in presence of 10 nM nilotinib by trypan blue dye exclusion counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4387605 | F | Inhibition of cell expansion in human KCL22 cells at 10 nM incubated for 48 hrs by trypan blue dye exclusion counting method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4387606 | F | Induction of cell cycle arrest in human KCL22 cells assessed as accumulation at G0-G1 phase at 3 uM incubated for 72 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 57.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4387607 | F | Induction of cell cycle arrest in human KCL22 cells assessed as accumulation at subG0 phase at 3 uM incubated for 72 hrs by propidium iodide staining based flow cytometry analysis (Rvb = 3.91%) | Homo sapiens | 1 | cell-based format | Scientific Literature |
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