# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3864862 | F | Induction of apoptosis in human KMS-12-BM cells assessed as increase in cleaved-PARP levels at 3.3 uM after 4 to 72 hrs by Western blot method | Homo sapiens | 1 | ALA3864151 | cell-based format | Scientific Literature | |
2. | ALA3864863 | F | Induction of apoptosis in human KMS-12-BM cells assessed as increase in cleaved caspase 3 levels at 3.3 uM after 4 to 72 hrs by Western blot method | Homo sapiens | 1 | ALA3864151 | cell-based format | Scientific Literature | |
3. | ALA3864864 | F | Induction of apoptosis in human KMS-12-BM cells assessed as increase in cleaved caspase 6 levels at 3.3 uM after 4 to 72 hrs by Western blot method | Homo sapiens | 1 | ALA3864151 | cell-based format | Scientific Literature | |
4. | ALA3864865 | F | Induction of apoptosis in human KMS-12-BM cells assessed as increase in cleaved caspase 7 levels at 3.3 uM after 4 to 72 hrs by Western blot method | Homo sapiens | 1 | ALA3864151 | cell-based format | Scientific Literature | |
5. | ALA4031337 | F | Antiproliferative activity against human KMS-12-BM cells after 48 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 5 | ALA4028864 | cell-based format | Scientific Literature | |
6. | ALA4031345 | F | Antiproliferative activity against human KMS-12-BM cells assessed as cell viability at 10 uM after 48 hrs by CellTiter-Glo luminescent assay relative to control | Homo sapiens | 1 | ALA4028864 | cell-based format | Scientific Literature | |
7. | ALA4031364 | F | Induction of apoptosis in human KMS-12-BM cells assessed as increase in cleaved PARP level at 1 to 6 uM after 24 hrs by immunoblotting analysis | Homo sapiens | 1 | ALA4028864 | cell-based format | Scientific Literature | |
8. | ALA4151157 | F | Antiproliferative activity against human KMS-12-BM cells after 7 days by cell-titer glo based luminescence assay | Homo sapiens | 1 | ALA4145660 | cell-based format | Scientific Literature | |
9. | ALA4194322 | F | Antiproliferative activity against human KMS-12-BM cells after 96 hrs by CellTiter-Glo luminescence assay | Homo sapiens | 12 | ALA4190357 | cell-based format | Scientific Literature | |
10. | ALA4268249 | F | Antiproliferative activity against human KMS-12-BM cells after 72 hrs by MTT assay | Homo sapiens | 11 | ALA4265943 | cell-based format | Scientific Literature | |
11. | ALA4315189 | F | Antiproliferative activity against human KMS-12-BM cells incubated for 48 hrs by CellTiter-Glo luminescent cell viability assay | Homo sapiens | 2 | ALA4311997 | cell-based format | Scientific Literature | |
12. | ALA4315213 | F | Effect on human KMS-12-BM cells assessed as inhibition in H3K9Me2 level at 2 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4311997 | cell-based format | Scientific Literature | |
13. | ALA4315214 | F | Effect on human KMS-12-BM cells assessed as increase in H3K9Me2 level at 2.5 to 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4311997 | cell-based format | Scientific Literature | |
14. | ALA4315215 | F | Effect on human KMS-12-BM cells assessed as increase in H3K9Me2 level at 2.5 to 5 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4311997 | cell-based format | Scientific Literature | |
15. | ALA4315216 | F | Effect on human KMS-12-BM cells assessed as increase in cleaved PARP level at 10 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4311997 | cell-based format | Scientific Literature | |
16. | ALA4370174 | F | Antiproliferative activity against human KMS-12-BM cells after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 2 | ALA4368910 | cell-based format | Scientific Literature | |
17. | ALA4370179 | F | Antitumor activity against human KMS-12-BM cells xenografted in po dosed SCID-beige mouse assessed as tumor growth inhibition administered once daily for 14 days and measured twice per week | Homo sapiens | 1 | ALA4368910 | organism-based format | Scientific Literature | |
18. | ALA4370180 | F | Antitumor activity against human KMS-12-BM cells xenografted in SCID-beige mouse assessed as tumor growth inhibition at 10 mg/kg, po administered once daily for 14 days measured twice per week relative to control | Homo sapiens | 1 | ALA4368910 | organism-based format | Scientific Literature | |
19. | ALA4370181 | F | Antitumor activity against human KMS-12-BM cells xenografted in SCID-beige mouse assessed as tumor growth inhibition at 25 mg/kg, po administered once daily for 14 days measured twice per week relative to control | Homo sapiens | 1 | ALA4368910 | organism-based format | Scientific Literature | |
20. | ALA4370182 | F | Antitumor activity against human KMS-12-BM cells xenografted in SCID-beige mouse assessed as tumor growth inhibition at 50 mg/kg, po administered once daily for 14 days measured twice per week relative to control | Homo sapiens | 1 | ALA4368910 | organism-based format | Scientific Literature |