# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2168454 | F | Inhibition of DNA synthesis in human LN18 cells assessed as inhibition of tritiated thymidine incorporation at 1 to 3 uM after 24 hrs by beta counting | Homo sapiens | 11 | ALA2163299 | cell-based format | Scientific Literature | |
2. | ALA2169408 | F | Inhibition of lipid synthesis in human LN18 cells assessed as [14C]acetate incorporation after 24 hrs by Beta-counting | Homo sapiens | 1 | ALA2163299 | cell-based format | Scientific Literature | |
3. | ALA2169411 | F | Induction of [14C]acetate incorporation in human LN18 cells at 2 uM after 24 hrs by Beta-counting in presence of 2.5 to 10 uM atorvastatin | Homo sapiens | 2 | ALA2163299 | cell-based format | Scientific Literature | |
4. | ALA2169413 | F | Induction of [14C]acetate incorporation in human LN18 cells at 2 uM after 24 hrs by Beta-counting | Homo sapiens | 2 | ALA2163299 | cell-based format | Scientific Literature | |
5. | ALA3802623 | F | Induction of DR5 expression in human LN18 cells after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3797089 | cell-based format | Scientific Literature | |
6. | ALA3804296 | F | Effect on DcR2 expression in human LN18 cells upto 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3797089 | cell-based format | Scientific Literature | |
7. | ALA3804300 | F | Effect on DcR1 expression in human LN18 cells upto 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3797089 | cell-based format | Scientific Literature | |
8. | ALA3804304 | F | Effect on DR4 expression in human LN18 cells upto 25 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA3797089 | cell-based format | Scientific Literature | |
9. | ALA4190815 | F | Cytotoxicity against human LN18 cells harboring TP53 mutation assessed as cell death at 20 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 16 | ALA4190186 | cell-based format | Scientific Literature | |
10. | ALA4190818 | F | Cytotoxicity against human LN18 cells harboring TP53 mutation after 48 hrs by MTT assay | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
11. | ALA4190820 | F | Induction of apoptosis in human LN18 cells harboring TP53 mutation assessed as increase in cleaved caspase-3 expression at 20 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
12. | ALA4190822 | F | Induction of apoptosis in human LN18 cells harboring TP53 mutation assessed as increase in cleaved caspase-8 expression at 20 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
13. | ALA4190824 | F | Induction of apoptosis in human LN18 cells harboring TP53 mutation assessed as increase in cleaved caspase-9 expression at 20 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
14. | ALA4190826 | F | Induction of apoptosis in human LN18 cells harboring TP53 mutation assessed as increase in cleaved PARP expression at 20 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
15. | ALA4190830 | A | Effect on H3K27me3 levels in human LN18 cells harboring TP53 mutation at 20 uM after 24 to 48 hrs by Western blot analysis | Homo sapiens | 3 | ALA4190186 | cell-based format | Scientific Literature | |
16. | ALA4322565 | F | Cytotoxicity against human LN18 cells assessed as reduction in cell viability at 0.0001 to 10 uM incubated for 72 hrs by AlamarBlue assay | Homo sapiens | 1 | ALA4321807 | cell-based format | Scientific Literature | |
17. | ALA4371215 | F | Antiproliferative activity against human LN18 cells | Homo sapiens | 2 | ALA4371003 | cell-based format | Scientific Literature | |
18. | ALA4838959 | F | Cytotoxicity against human LN-18 cells assessed as reduction in cell viability at 5 uM after 72 hrs by MTT assay | Homo sapiens | 1 | ALA4837235 | cell-based format | Scientific Literature | |
19. | ALA4838989 | F | Cytotoxicity against human LN-18 cells assessed as reduction in cell viability at 5 uM after 24 to 72 hrs by MTT assay | Homo sapiens | 1 | ALA4837235 | cell-based format | Scientific Literature | |
20. | ALA5131821 | T | Cytotoxicity against human LN-18 cells | Homo sapiens | 1 | ALA5131375 | cell-based format | Scientific Literature |