# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4381266 | Functional | Antiproliferative activity against human LN229 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 8 | ALA4376884 | cell-based format | Scientific Literature | |
2. | ALA4381279 | Functional | Induction of cell morphological changes in human LN229 cells assessed as random membrane blebbing at 10 uM incubated for 24 to 48 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
3. | ALA4381280 | Functional | Induction of cell morphological changes in human LN229 cells assessed as loss of cell adherence at 10 uM incubated for 24 to 48 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
4. | ALA4381282 | Functional | Induction of cell morphological changes in human LN229 cells assessed as cell rounding at 10 uM incubated for 24 to 48 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
5. | ALA4381284 | Functional | Induction of cell morphological changes in human LN229 cells assessed as cell shrinkage at 10 uM incubated for 24 to 48 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
6. | ALA4381289 | Functional | Antiproliferative activity against human LN229 cells assessed as reduction in cell viability incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
7. | ALA4381297 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at G1 phase at 10 uM incubated for 24 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
8. | ALA4381298 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at S phase at 10 uM incubated for 24 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
9. | ALA4381299 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at G2/M phase at 10 uM incubated for 24 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
10. | ALA4381300 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at G1 phase at 10 uM incubated for 48 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
11. | ALA4381301 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at S phase at 10 uM incubated for 48 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
12. | ALA4381302 | Functional | Cell cycle arrest in human LN229 cells assessed as cell accumulation at G2/M phase at 10 uM incubated for 48 hrs by propidium iodide staining based flow cytometry analysis relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
13. | ALA4381309 | Functional | Induction of cellular senescence in human LN229 cells assessed as increase in beta-gal-positive cells at 10 uM incubated for 24 hrs by X-Gal staining based microscopic assay relative to control | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
14. | ALA4381311 | Functional | Induction of cellular senescence in human LN229 cells assessed as flattened cells at 10 uM incubated for 24 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
15. | ALA4381312 | Functional | Induction of cellular senescence in human LN229 cells assessed as wider cells at 10 uM incubated for 24 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
16. | ALA4381313 | Functional | Induction of cellular senescence in human LN229 cells assessed as cells with irregular shape at 10 uM incubated for 24 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
17. | ALA4381314 | Functional | Induction of cellular senescence in human LN229 cells assessed as larger volume of cell at 10 uM incubated for 24 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
18. | ALA4381315 | Functional | Induction of cellular senescence in human LN229 cells assessed as increase in nuclear size at 10 uM incubated for 24 hrs by phase contrast microscopy | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
19. | ALA4381331 | Functional | Induction of apoptosis in human LN229 cells assessed as increase in caspase-3/7 activation at 10 uM incubated for 48 hrs by luminometric caspase-glo 3/7 assay | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
20. | ALA4381333 | Functional | Induction of mitochondrial membrane potential loss in human LN229 cells at 10 uM measured upto 48 hrs by JC-1 staining based flow cytometry analysis | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature |