# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA853953 | Functional | Inhibition of HIF1-alpha production in c4-2 cells at 20 nM after 24 hrs relative to control | Homo sapiens | 1 | ALA1139736 | cell-based format | Scientific Literature | |
2. | ALA853954 | Functional | Inhibition of HIF1alpha production in c4-2 cells at 10 uM after 24 hrs relative to control | Homo sapiens | 7 | ALA1139736 | cell-based format | Scientific Literature | |
3. | ALA853955 | Functional | Inhibition of HIF1-alpha production in c4-2 cells at 10 nM after 24 hrs relative to control | Homo sapiens | 1 | ALA1139736 | cell-based format | Scientific Literature | |
4. | ALA4418078 | Functional | Cytotoxicity against human C4-2 cells assessed as reduction in cell viability incubated for 7 days | Homo sapiens | 1 | ALA4417634 | cell-based format | Patent Bioactivity Data | |
5. | ALA2174894 | Functional | Induction of apoptosis in human C4-2 cells expressing Luc-BAD assessed as increase in cleavage of PARP at 3 to 50 uM after 6 hrs by Western blotting | Homo sapiens | 1 | ALA2169799 | cell-based format | Scientific Literature | |
6. | ALA2174895 | Functional | Induction of apoptosis in human C4-2 cells expressing Luc-BAD assessed as increase in caspase activity at 3 to 50 uM after 6 hrs by Caspase 3 assay | Homo sapiens | 1 | ALA2169799 | cell-based format | Scientific Literature | |
7. | ALA3999919 | Functional | Cytotoxicity against human C4-2 cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 21 | ALA3997843 | cell-based format | Scientific Literature | |
8. | ALA3999925 | Functional | Induction of apoptosis in human C4-2 cells assessed as increase in cleaved PARP expression by measuring ratio of cleaved PARP to actin level after 48 hrs by immunoblot method relative to control | Homo sapiens | 3 | ALA3997843 | cell-based format | Scientific Literature | |
9. | ALA3999926 | Functional | Induction of apoptosis in human C4-2 cells assessed as increase in nuclear fragmentation at 8 uM after 24 hrs by acridine orange/ethidium bromide staining based fluorescent microscopic method | Homo sapiens | 1 | ALA3997843 | cell-based format | Scientific Literature | |
10. | ALA3999927 | Functional | Induction of apoptosis in human C4-2 cells assessed as increase in nuclear fragmentation at 7 uM after 24 hrs by acridine orange/ethidium bromide staining based fluorescent microscopic method | Homo sapiens | 1 | ALA3997843 | cell-based format | Scientific Literature | |
11. | ALA4130945 | Functional | Antiproliferative activity against human C4-2 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4130348 | cell-based format | Scientific Literature | |
12. | ALA4221007 | Functional | Antiproliferative activity against human AR positive C4-2 cells at 50 uM after 72 hrs by MTS assay relative to control | Homo sapiens | 1 | ALA4219079 | cell-based format | Scientific Literature | |
13. | ALA4221009 | Functional | Antiproliferative activity against human AR positive C4-2 cells up to 25 uM after 72 hrs by MTS assay | Homo sapiens | 1 | ALA4219079 | cell-based format | Scientific Literature | |
14. | ALA4221012 | Functional | Antiproliferative activity against human AR positive C4-2 cells at 1.25 uM after 72 hrs by MTS assay relative to control | Homo sapiens | 1 | ALA4219079 | cell-based format | Scientific Literature | |
15. | ALA4222812 | Functional | Cytotoxicity against human C4-2 cells after 48 hrs by MTT assay | Homo sapiens | 17 | ALA4219171 | cell-based format | Scientific Literature | |
16. | ALA4235117 | Functional | Growth inhibition of human C4-2 cells after 48 hrs by MTT assay | Homo sapiens | 14 | ALA4229493 | cell-based format | Scientific Literature | |
17. | ALA4235122 | Functional | Induction of apoptosis in human C4-2 cells assessed as nuclear fragmentation at 2.5 uM after 48 hrs by acridine orange/ethidium bromide staining based inverted fluorescent microscopic method | Homo sapiens | 1 | ALA4229493 | cell-based format | Scientific Literature | |
18. | ALA4235123 | Functional | Induction of apoptosis in human C4-2 cells assessed as nuclear fragmentation at 3.5 uM after 48 hrs by acridine orange/ethidium bromide staining based inverted fluorescent microscopic method | Homo sapiens | 1 | ALA4229493 | cell-based format | Scientific Literature | |
19. | ALA4235124 | Functional | Induction of apoptosis in human C4-2 cells assessed as PARP cleavage at 2.5 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4229493 | cell-based format | Scientific Literature | |
20. | ALA4235125 | Functional | Induction of apoptosis in human C4-2 cells assessed as PARP cleavage at 3.5 uM after 48 hrs by Western blot analysis | Homo sapiens | 1 | ALA4229493 | cell-based format | Scientific Literature |