| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3136010 | F | Inhibition of oestrogen, progesterone and HER2/neu receptor triple negative human MDA-MB-436 cell proliferation assessed as [3H]thymidine incorporation into DNA helix after 3 days by betaplate counting analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA4022435 | F | Cytotoxicity against human MDA-MB-436 cells assessed as decrease in cell viability after 120 hrs by MTS assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA4050172 | F | Antiproliferative activity against human MDA-MB-436 cells assessed as reduction in cell viability after 5 to 7 days by CellTiter 96 aqueous solution assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 4. | ALA4131014 | F | Antiproliferative activity against human MDA-MB-436 cells after 7 days by CCK8 or SRB assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 5. | ALA4131037 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as early apoptotic cells at 0.1 uM after 96 hrs by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 1.90%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4131038 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as late apoptotic cells at 0.1 uM after 96 hrs by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 5.61%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4131039 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as early apoptotic cells at 1 uM after 96 hrs by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 1.90%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA4131040 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as late apoptotic cells at 1 uM after 96 hrs by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 5.61%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA4131041 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as early apoptotic cells at 0.1 uM after 96 hrs in presence of pancaspase inhibitor Z-VAD-FMK by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 2.32%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA4131042 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as late apoptotic cells at 0.1 uM after 96 hrs in presence of pancaspase inhibitor Z-VAD-FMK by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 5.11%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4131043 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as early apoptotic cells at 1 uM after 96 hrs in presence of pancaspase inhibitor Z-VAD-FMK by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 2.32%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA4131044 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as late apoptotic cells at 1 uM after 96 hrs in presence of pancaspase inhibitor Z-VAD-FMK by Annexin V-FITC/propidium iodide double-staining based flow cytometery (Rvb = 5.11%) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4131046 | F | Induction of apoptosis in human MDA-MB-436 cells after 96 hrs by Annexin V-FITC/propidium iodide double-staining based flow cytometery | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4131047 | F | Antitumor activity against human MDA-MB-436 cells harboring BRCA1 mutant xenografted in nude BALB/cA mouse assessed as tumor growth inhibition at 50 mg/kg, po administered once daily for 21 consecutive days measured twice per week | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4131048 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as caspase-3/7 activation at 0.1 to 1 uM after 72 hrs by Caspase-Glo 3/7 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4131049 | F | Antitumor activity against human MDA-MB-436 cells harboring BRCA1 mutant xenografted in nude BALB/cA mouse assessed as tumor growth inhibition at 100 mg/kg, po administered once daily for 21 consecutive days measured twice per week | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4133755 | F | Antiproliferative activity against human MDA-MB-436 cells incubated for 24 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4143139 | F | Antiproliferative activity against human MDA-MB-436 cells assessed as decrease in cell viability after 24 hrs by MTT assay | Homo sapiens | 48 | cell-based format | Scientific Literature | ||
| 19. | ALA4143141 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as membrane blebbing by phase contrast microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4143143 | F | Induction of apoptosis in human MDA-MB-436 cells assessed as formation of apoptotic bodies by phase contrast microscopy | Homo sapiens | 1 | cell-based format | Scientific Literature |
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