# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4008960 | A | Apparent inward permeability in MDCK2-MDR1 cells | Canis lupus familiaris | 1 | ALA4007421 | cell-based format | Scientific Literature | |
2. | ALA4018097 | A | Apparent permeability in MDCK2-MDR1 cells at 5 uM after 1 hr by LC-MS/MS method | Canis lupus familiaris | 1 | ALA4017471 | cell-based format | Scientific Literature | |
3. | ALA4018315 | A | Apparent permeability from apical to basolateral side in MDCK2-MDR1 cells at 2 uM after 2.5 hrs LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA4017480 | cell-based format | Scientific Literature | |
4. | ALA4018316 | A | Efflux ratio of apparent permeability from basolateral to apical over apical to basolateral side in MDCK2-MDR1 cells at 2 uM after 2.5 hrs LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA4017480 | cell-based format | Scientific Literature | |
5. | ALA4028576 | A | Apparent passive permeability from apical to basolateral side in MDCK2-MDR1 cells at 3 uM after 90 mins by LC-MS/MS analysis | Canis lupus familiaris | 2 | ALA4024800 | cell-based format | Scientific Literature | |
6. | ALA4030187 | A | Efflux ratio of permeability in MDCK2-MDR1 cells | Canis lupus familiaris | 4 | ALA4028836 | cell-based format | Scientific Literature | |
7. | ALA4035875 | A | Efflux ratio of permeability in MDCK2-MDR1 cells | Canis lupus familiaris | 3 | ALA4033702 | cell-based format | Scientific Literature | |
8. | ALA4037526 | A | Efflux ratio of passive permeability in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins by Transwell assay | Canis lupus familiaris | 26 | ALA4033786 | cell-based format | Scientific Literature | |
9. | ALA4037527 | A | Passive permeability in MDCK2-MDR1 cells transduced with BacMam2-BCRP at 3 uM after 90 mins by Transwell assay | Canis lupus familiaris | 33 | ALA4033786 | cell-based format | Scientific Literature | |
10. | ALA4045589 | A | Passive permeability in MDCK2-MDR1 cells in presence of P-gp inhibitor | Canis lupus familiaris | 1 | ALA4043167 | cell-based format | Scientific Literature | |
11. | ALA4046304 | A | Apparent permeability in MDCK2-MDR1 cells at 3 uM incubated for 1 hr in presence of P-glycoprotein inhibitor GF120918 by LC/MS/MS method | Canis lupus familiaris | 26 | ALA4043178 | cell-based format | Scientific Literature | |
12. | ALA4046307 | A | Apparent permeability in MDCK2-MDR1 cells at 3 uM incubated for 1 hr in absence of P-glycoprotein inhibitor GF120918 by LC/MS/MS method | Canis lupus familiaris | 4 | ALA4043178 | cell-based format | Scientific Literature | |
13. | ALA4051325 | A | Efflux ratio of permeability in MDCK2-MDR1 cells at 10 uM | Canis lupus familiaris | 4 | ALA4049430 | cell-based format | Scientific Literature | |
14. | ALA4363680 | F | Cytotoxicity against dog MDCK-MDR1 cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay | Canis lupus familiaris | 1 | ALA4359914 | cell-based format | Scientific Literature | |
15. | ALA4363682 | F | Induction of ROS-mediated cell death in dog MDCK-MDR1 cells at 500 nM incubated for 24 hrs by DCFDA-AM staining based ATPlite luminescence assay | Canis lupus familiaris | 1 | ALA4359914 | cell-based format | Scientific Literature | |
16. | ALA4363684 | F | Induction of ROS-mediated cell death in dog MDCK-MDR1 cells at 500 nM incubated for 24 hrs in presence of NAC by DCFDA-AM staining based ATPlite luminescence assay | Canis lupus familiaris | 1 | ALA4359914 | cell-based format | Scientific Literature | |
17. | ALA4363691 | F | Induction of ROS generation in dog MDCK-MDR1 cells at 500 nM incubated for 24 hrs by DCFDA-AM staining based ATPlite luminescence assay | Canis lupus familiaris | 2 | ALA4359914 | cell-based format | Scientific Literature | |
18. | ALA4372257 | A | Ratio of permeability across apical to basolateral side in MDCK2-MDR1 cells transduced with BacMam2-BCRP in presence of P-gp inhibitor GF120918 to absence of GF120918 | Canis lupus familiaris | 15 | ALA4371037 | cell-based format | Scientific Literature | |
19. | ALA4372259 | A | Ratio of permeability across apical to basolateral side in MDCK2-MDR1 cells in presence of P-gp inhibitor GF120918 to absence of GF120918 | Canis lupus familiaris | 5 | ALA4371037 | cell-based format | Scientific Literature | |
20. | ALA4391178 | A | Cytotoxicity against MDCK2-MDR1 cells assessed as reduction in cell viability at 75 uM incubated for 2 hrs by MTT assay | Canis lupus familiaris | 3 | ALA4390652 | cell-based format | Scientific Literature |