| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4252564 | F | Antiproliferative activity against human MM473 cells at 10 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | ALA4251569 | cell-based format | Scientific Literature | |
| 2. | ALA4252573 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G0/G1 phase at 4 uM after 24 hrs by propidium iodide staining-based flow cytometric method (Rvb = 54.5%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 3. | ALA4252574 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at S phase at 4 uM after 24 hrs by propidium iodide staining-based flow cytometric method (Rvb = 29.8%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 4. | ALA4252575 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G2/M at 4 uM after 24 hrs by propidium iodide staining-based flow cytometric method (Rvb = 15.7%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 5. | ALA4252576 | F | Induction of apoptosis in human MM473 cells at 4 uM after 24 hrs by propidium iodide staining-based flow cytometric method (Rvb = 2.5%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 6. | ALA4252577 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G0/G1 phase at 4 uM after 48 hrs by propidium iodide staining-based flow cytometric method (Rvb = 71.8%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 7. | ALA4252578 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at S phase at 4 uM after 48 hrs by propidium iodide staining-based flow cytometric method (Rvb = 23.9%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 8. | ALA4252579 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G2/M phase at 4 uM after 48 hrs by propidium iodide staining-based flow cytometric method (Rvb = 4.3%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 9. | ALA4252580 | F | Induction of apoptosis in human MM473 cells at 4 uM after 48 hrs by propidium iodide staining-based flow cytometric method (Rvb = 2.2%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 10. | ALA4252581 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G0/G1 phase at 4 uM after 72 hrs by propidium iodide staining-based flow cytometric method (Rvb = 80.2%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 11. | ALA4252582 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at S phase at 4 uM after 72 hrs by propidium iodide staining-based flow cytometric method (Rvb = 15.1%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 12. | ALA4252583 | F | Cell cycle arrest in human MM473 cells assessed as accumulation at G2/M phase at 4 uM after 72 hrs by propidium iodide staining-based flow cytometric method (Rvb = 4.6%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 13. | ALA4252584 | F | Induction of apoptosis in human MM473 cells at 4 uM after 72 hrs by propidium iodide staining-based flow cytometric method (Rvb = 1.4%) | Homo sapiens | 1 | ALA4251569 | cell-based format | Scientific Literature | |
| 14. | ALA4252597 | F | Antitumor activity against human MM473 cells xenografted in CD1 nude mouse assessed as inhibition of tumor volume at 20 mg/kg, iv administered every 4 days per week for 3 weeks measured 10 days post last dose by luciferase reporter assay relative to vehicle-treated control | Homo sapiens | 1 | ALA4251569 | organism-based format | Scientific Literature | |
| 15. | ALA4252598 | F | Antitumor activity against human MM473 cells xenografted in CD1 nude mouse assessed as inhibition of tumor volume at 90 mg/kg, iv administered every 4 days per week for 3 weeks measured 10 days post last dose by luciferase reporter assay relative to vehicle-treated control | Homo sapiens | 1 | ALA4251569 | organism-based format | Scientific Literature | |
| 16. | ALA5155477 | F | Antiproliferative activity against human MM473 cells incubated for 24 hrs followed by incubating in drug-free medium for 48 hrs and measured by SRB assay | Homo sapiens | 4 | ALA5154648 | cell-based format | Scientific Literature | |
| 17. | ALA5155507 | F | Induction of DNA damage in human MM473 cells at 0.1 to 0.4 uM assessed as increase in p-H2AX levels and measured by Western blot analysis | Homo sapiens | 1 | ALA5154648 | cell-based format | Scientific Literature | |
| 18. | ALA5155512 | F | Induction of DNA damage in human MM473 cells at 7.4 uM assessed as increase in p-H2AX levels and measured by Western blot analysis | Homo sapiens | 1 | ALA5154648 | cell-based format | Scientific Literature | |
| 19. | ALA5155539 | F | Induction of cell cycle arrest in human MM473-Luc cells assessed as accumulation of cells at sub-G1 phase at 1.2 uM after 72 hrs by flow cytometry (Rvb = 1.3%) | Homo sapiens | 1 | ALA5154648 | cell-based format | Scientific Literature | |
| 20. | ALA5155540 | F | Induction of cell cycle arrest in human MM473-Luc cells assessed as accumulation of cells at G0/1 phase at 1.2 uM after 72 hrs by flow cytometry (Rvb = 74.7%) | Homo sapiens | 1 | ALA5154648 | cell-based format | Scientific Literature |
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