# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2045569 | F | Induction of apoptosis in human Mahlavu cells assessed as PARP cleavage into 89 kDa and 24 kDa fragments at 9.2 uM after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA2040791 | cell-based format | Scientific Literature | |
2. | ALA2045575 | F | Induction of necrosis in human Mahlavu cells assessed as PARP cleavage into 50 kDa fragment at 9.2 uM after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA2040791 | cell-based format | Scientific Literature | |
3. | ALA3380246 | F | Induction of apoptosis in human Mahlavu cells assessed as PARP cleavage at IC50 after 72 hrs by Western blotting analysis | Homo sapiens | 3 | ALA3352193 | cell-based format | Scientific Literature | |
4. | ALA3380247 | F | Induction of necrosis in human Mahlavu cells assessed as PARP cleavage at IC50 after 72 hrs by Western blotting analysis | Homo sapiens | 3 | ALA3352193 | cell-based format | Scientific Literature | |
5. | ALA3380248 | F | Induction of apoptosis in human Mahlavu cells assessed as Bcl2 expression at IC50 after 72 hrs by Western blotting analysis | Homo sapiens | 3 | ALA3352193 | cell-based format | Scientific Literature | |
6. | ALA3380249 | F | Induction of apoptosis in human Mahlavu cells assessed as total cytochrome c level at IC50 after 72 hrs by Western blotting analysis | Homo sapiens | 3 | ALA3352193 | cell-based format | Scientific Literature | |
7. | ALA3380251 | F | Reduction in intrinsic cellular ATP consumption in human Mahlavu cells at IC50 after 24 hrs by bioluminescence assay | Homo sapiens | 3 | ALA3352193 | cell-based format | Scientific Literature | |
8. | ALA3757487 | F | Induction of apoptosis in human Mahlavu cells assessed as decrease in cyclin D1 level after 24 to 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA3751842 | cell-based format | Scientific Literature | |
9. | ALA3757495 | F | Induction of apoptosis in human Mahlavu cells assessed as PARP cleavage after 24 to 48 hrs by Western blot analysis | Homo sapiens | 2 | ALA3751842 | cell-based format | Scientific Literature | |
10. | ALA3757498 | F | Induction of oxidative stress in human Mahlavu cells assessed as ROS accumulation at 10 uM after 48 hrs by DCFH-DA staining based fluorescence microscopy | Homo sapiens | 2 | ALA3751842 | cell-based format | Scientific Literature | |
11. | ALA3757499 | F | Induction of oxidative stress in human Mahlavu cells assessed as ROS accumulation at 10 uM after 48 hrs by flow cytometry analysis | Homo sapiens | 2 | ALA3751842 | cell-based format | Scientific Literature | |
12. | ALA3769115 | F | Induction of apoptosis in human Mahlavu cells assessed as cleavage of PARP protein at IC50 after 72 hrs by Western blot analysis | Homo sapiens | 1 | ALA3763025 | cell-based format | Scientific Literature | |
13. | ALA4006881 | F | Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by SRB assay | Homo sapiens | 4 | ALA4004857 | cell-based format | Scientific Literature | |
14. | ALA4006887 | F | Growth inhibition of human Mahlavu cells at cytotoxic IC100 measured every 10 mins for first 24 hrs and every 30 mins for remaining 48 hrs by RT-CES analysis | Homo sapiens | 4 | ALA4004857 | cell-based format | Scientific Literature | |
15. | ALA4138353 | F | Cytotoxicity against human Mahlavu cells assessed as growth inhibition after 72 hrs by SRB assay | Homo sapiens | 12 | ALA4138043 | cell-based format | Scientific Literature | |
16. | ALA4138357 | F | Disruption of cancer stem cell subpopulation of human Mahlavu cells assessed as aggressiveness factor at IC100 after 72 hrs by flow cytometric method | Homo sapiens | 7 | ALA4138043 | cell-based format | Scientific Literature | |
17. | ALA4138363 | F | Disruption of cancer stem cell subpopulation of human Mahlavu cells assessed as effect on CD90 levels at IC100 after 72 hrs by flow cytometric method (Rvb = 0.6%) | Homo sapiens | 7 | ALA4138043 | cell-based format | Scientific Literature | |
18. | ALA4185133 | F | Antiproliferative activity against human Mahlavu cells after 72 hrs by SRB assay | Homo sapiens | 11 | ALA4184126 | cell-based format | Scientific Literature | |
19. | ALA4317088 | F | Cytotoxicity against human Mahlavu cells after 72 hrs by SRB assay | Homo sapiens | 10 | ALA4316592 | cell-based format | Scientific Literature | |
20. | ALA4317100 | F | Cytotoxicity against human Mahlavu cells after 24 hrs by RTCA analysis | Homo sapiens | 2 | ALA4316592 | cell-based format | Scientific Literature |