| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3424552 | F | Inhibition of autophagy in human NCI-H3122 cells assessed as increase in punctate LC3 expression at 25 to 50 uM after 6 hrs by fluorescence microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3993034 | F | Antitumor activity against human NCI-H3122 cells xenografted in BALB/c nu/nu mouse assessed as reduction in tumor volume at 50 mg/kg administered via oral gavage for 14 days | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA4017796 | F | Antitumor activity against human NCI-H3122 cells xenografted in BALB/c nu/nu mouse assessed as tumor growth inhibition at 50 mg/kg administered once daily via oral gavage for 14 days measured twice weekly during compound dosing relative to control | Homo sapiens | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA4017799 | F | Antitumor activity against human NCI-H3122 cells xenografted in BALB/c nu/nu mouse at 50 mg/kg administered once daily via oral gavage for 14 days measured after treatment discontinuation | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA4041761 | F | Antiproliferative activity against human NCI-H3122 cells after 72 hrs by SRB assay | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
| 6. | ALA4041772 | F | Potency index, ratio of AUY922 IC50 to compound IC50 for human NCI-H3122 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4142799 | F | Antiproliferative activity against human NCI-H3122 cells after 48 hrs by MTT assay | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 8. | ALA4145699 | F | Growth inhibition of human NCI-H3122 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 9. | ALA4145733 | F | Antiproliferative activity against human NCI-H3122 cells harboring EML4-fused ALK varian1 after 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA4145766 | F | Cell cycle arrest in human NCI-H3122 cells assessed as accumulation at G0/G1 phase at 0.03 to 0.3 uM after 24 hrs by propidium iodide/RNase staining-based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4145772 | F | Induction of apoptosis in human NCI-H3122 cells assessed as increase in cleaved PARP expression level at 300 nM after 24 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4145773 | F | Induction of apoptosis in human NCI-H3122 cells assessed as increase in cleaved caspase-3 expression level at 300 nM after 24 hrs by Western blot method | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4145783 | F | Antitumor activity against human NCI-H3122 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 10 mg/kg, po qd administered for 28 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4145784 | F | Antitumor activity against human NCI-H3122 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 20 mg/kg, po qd administered for 28 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4145785 | F | Antitumor activity against human NCI-H3122 cells xenografted in nu/nu mouse assessed as tumor growth inhibition at 40 mg/kg, po qd administered for 28 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA4145786 | F | Antitumor activity against human NCI-H3122 cells xenografted in po dosed nu/nu mouse assessed as tumor growth inhibition administered for 28 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA4145787 | F | Antitumor activity against human NCI-H3122 cells xenografted in po dosed nu/nu mouse assessed as decrease in cell proliferation administered for 28 days by Ki67 staining-based immunohistochemical analysis | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA4145788 | F | Induction of apoptosis in human NCI-H3122 cells xenografted in po dosed nu/nu mouse administered for 28 days by DAB-chromogen-based TUNEL assay | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA4146208 | F | Antiproliferative activity against human NCI-H3122 cells after 72 hrs by SRB or CCK8 assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 20. | ALA4146248 | F | Induction of apoptosis in human NCI-H3122 cells at 20 to 80 nM after 48 hrs by Annexin V-FITC/propidium iodide staining based flow cytometry | Homo sapiens | 1 | cell-based format | Scientific Literature |
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