| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1838127 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells assessed as PGE2 level per 1000 cells at 0.1 uM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA (Rvb = 3.15 +/- 0.19 pg/mL) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA1838128 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells assessed as PGE2 level per 1000 cells at 1 uM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA (Rvb = 3.15 +/- 0.19 pg/mL) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA1838635 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells assessed as PGE2 level per 1000 cells at 10 uM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA (Rvb = 3.15 +/- 0.19 pg/mL) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA1838639 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells at 100 nM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA1838640 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells at 1 uM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA1838641 | F | Inhibition of sodium arachidonate-induced PGE2 production in human SUM149 cells at 10 uM preincubated for 2 hrs before sodium arachidonate challenge measured after 2 hrs by competitive EIA | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3369143 | F | Induction of PTPN6 mRNA expression in human SUM149PT cells after 24 hrs by RT-PCR analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4185407 | F | Cytotoxicity against human SUM149PT cells assessed as cell growth inhibition after 4 days by WST-8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4196342 | F | Antiproliferative activity against human SUM149PT cells after 48 hrs by SRB assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 10. | ALA4196344 | F | Cell cycle arrest in human SUM149PT cells assessed as increase in cells at G1 phase after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4196345 | F | Cell cycle arrest in human SUM149PT cells assessed as decrease in cells at S phase at 5 to 10 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4196346 | F | Inhibition of KLF5 expression levels in human SUM149PT cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA4196348 | F | Induction of PARP cleavage in human SUM149PT cells after 24 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA4196359 | F | Cell cycle arrest in human SUM149PT cells assessed as increase in cells at G1 phase at 20 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4196360 | F | Cell cycle arrest in human SUM149PT cells assessed as decrease in cells at S phase at 20 uM after 24 hrs by propidium iodide staining-based flow cytometric analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4305074 | F | Cytotoxicity against BRCA1-proficient human SUM149 cells measured after 6 days by microscopic analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4305075 | F | Selectivity ratio of EC50 for BRCA1-proficient human SUM149 cells to EC50 for BRCA1-deficient human SUM149 cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4305076 | F | Cytotoxicity against BRCA1-deficient human SUM149 cells measured after 6 days by microscopic analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4335561 | F | Antiproliferative activity against human SUM149 cells assessed as reduction in cell viability at >10 uM after 48 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4335577 | F | Antiproliferative activity against human SUM149 cells assessed as reduction in cell viability at 0.1 to 250 uM after 48 hrs by propidium iodide staining based fluorescence assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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