# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3111919 | F | Inhibition of PRMT1 gene expression in androgen-stimulated human VCaP cells by RT-PCR analysis | Homo sapiens | 1 | ALA3108746 | cell-based format | Scientific Literature | |
2. | ALA3112255 | F | Inhibition of AR gene expression in R1881-stimulated human VCaP cells at 1.56 to 100 uM by RT-PCR analysis | Homo sapiens | 1 | ALA3108746 | cell-based format | Scientific Literature | |
3. | ALA4045239 | F | Antiproliferative activity against human VCaP cells | Homo sapiens | 1 | ALA4043145 | cell-based format | Scientific Literature | |
4. | ALA4152056 | F | Growth inhibition of human VCaP cells overexpressing TMPRSS2-ERG gene incubated for 72 hrs by resazurin based assay | Homo sapiens | 10 | ALA4145693 | cell-based format | Scientific Literature | |
5. | ALA4154892 | F | Antiproliferative activity against human VCaP cells treated at 12 hrs post cell seeding measured at 72 to 144 hrs post cell seeding by Cell-Titer Glo assay | Homo sapiens | 11 | ALA4152259 | cell-based format | Scientific Literature | |
6. | ALA4190495 | F | Antitumor activity against human VCaP cells xenografted in SCID mouse assessed as tumor growth inhibition at 10 mg/kg, sc administered every 3 days for 16 days relative to control | Homo sapiens | 1 | ALA4190166 | organism-based format | Scientific Literature | |
7. | ALA4191532 | F | Antiproliferative activity against human VCaP cells expressing androgen receptor splice variants assessed as decrease in cell viability after 5 days by trypan blue exclusion assay | Homo sapiens | 4 | ALA4190216 | cell-based format | Scientific Literature | |
8. | ALA4219490 | F | Cytotoxicity against human VCaP cells at 3 uM after 48 hrs by WST-8 assay | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
9. | ALA4219498 | F | Induction of morphological changes in human VCaP cells at 3 uM after 24 hrs by phase contrast microscopic analysis | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
10. | ALA4219499 | F | Induction of apoptosis in human VCaP cells assessed as caspase-3 activation at 1 to 3 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
11. | ALA4219500 | F | Induction of apoptosis in human VCaP cells assessed as increase in cleaved PARP levels at 1 to 3 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
12. | ALA4219501 | F | Induction of apoptosis in human VCaP cells assessed as caspase-3 activation at 1 to 3 uM in presence of pan-caspase inhibitor zVAD-FMK after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
13. | ALA4219502 | F | Induction of apoptosis in human VCaP cells assessed as increase in cleaved PARP levels at 1 to 3 uM in presence of pan-caspase inhibitor zVAD-FMK after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
14. | ALA4219503 | F | Induction of apoptosis in human VCaP cells assessed as viable cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 98.9%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
15. | ALA4219504 | F | Induction of apoptosis in human VCaP cells assessed as early apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 0.5%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
16. | ALA4219505 | F | Induction of apoptosis in human VCaP cells assessed as late apoptotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 0.1%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
17. | ALA4219506 | F | Induction of apoptosis in human VCaP cells assessed as necrotic cells at 3 uM after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 0.5%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
18. | ALA4219507 | F | Induction of apoptosis in human VCaP cells assessed as viable cells at 3 uM in presence of pan-caspase inhibitor zVAD-FMK after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 98.9%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
19. | ALA4219508 | F | Induction of apoptosis in human VCaP cells assessed as early apoptotic cells at 3 uM in presence of pan-caspase inhibitor zVAD-FMK after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 0.5%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature | |
20. | ALA4219509 | F | Induction of apoptosis in human VCaP cells assessed as late apoptotic cells at 3 uM in presence of pan-caspase inhibitor zVAD-FMK after 24 hrs by Annexin V-FITC/propidium iodide staining-based flow cytometry (Rvb = 0.1%) | Homo sapiens | 1 | ALA4219028 | cell-based format | Scientific Literature |