# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4146482 | F | Induction of elastin synthesis in rat VSMC at 50 uM after 48 hrs by ELISA relative to control | Rattus norvegicus | 5 | ALA4145465 | cell-based format | Scientific Literature | |
2. | ALA4146483 | F | Induction of elastin synthesis in rat VSMC at 20 uM after 48 hrs by ELISA | Rattus norvegicus | 5 | ALA4145465 | cell-based format | Scientific Literature | |
3. | ALA4191640 | A | Cytotoxicity against Sprague-Dawley rat VSMC assessed as decrease in cell viability at >5 uM after 24 hrs by MTT assay | Rattus norvegicus | 1 | ALA4190221 | cell-based format | Scientific Literature | |
4. | ALA4191641 | A | Cytotoxicity against Sprague-Dawley rat VSMC assessed as decrease in cell viability at 5 to 10 uM after 24 hrs by MTT assay | Rattus norvegicus | 6 | ALA4190221 | cell-based format | Scientific Literature | |
5. | ALA4191642 | A | Cytotoxicity against Sprague-Dawley rat VSMC assessed as decrease in cell viability at 0.5 to 1 uM after 24 hrs by MTT assay | Rattus norvegicus | 1 | ALA4190221 | cell-based format | Scientific Literature | |
6. | ALA4191643 | F | Inhibition of PDGF-induced Sprague-Dawley rat VSMC proliferation at 10 uM pretreated for 2 hrs followed by PDGF stimulation measured after 24 hrs by MTT assay relative to control | Rattus norvegicus | 2 | ALA4190221 | cell-based format | Scientific Literature | |
7. | ALA4191644 | F | Inhibition of PDGF-induced Sprague-Dawley rat VSMC proliferation at 5 to 10 uM pretreated for 2 hrs followed by PDGF stimulation measured after 24 hrs by MTT assay | Rattus norvegicus | 3 | ALA4190221 | cell-based format | Scientific Literature | |
8. | ALA4191676 | F | Inhibition of PDGF-BB-induced rat VSMC proliferation preincubated for 30 mins followed by PDGF-BB addition measured after 48 hrs by resazurin assay | Rattus norvegicus | 1 | ALA4190224 | cell-based format | Scientific Literature | |
9. | ALA4191677 | A | Cytotoxicity against rat VSMC at 1 to 15 uM after 48 hrs by LDH release assay | Rattus norvegicus | 1 | ALA4190224 | cell-based format | Scientific Literature | |
10. | ALA4191678 | F | Antimigratory activity against PDGF-BB-stimulated rat VSMC at 15 uM preincubated for 30 mins followed by PDGF-BB addition measured after 20 hrs by scratch wound-healing assay | Rattus norvegicus | 1 | ALA4190224 | cell-based format | Scientific Literature | |
11. | ALA4264017 | A | Cytotoxicity against human VSMC assessed as cell viability at 100 uM after 24 hrs by MTT assay | Homo sapiens | 4 | ALA4261598 | cell-based format | Scientific Literature | |
12. | ALA4264018 | F | Induction of NO release in human VSMC assessed as intracellular S-nitrosothiol level at 100 uM after 1 hr by fluorimetric method | Homo sapiens | 4 | ALA4261598 | cell-based format | Scientific Literature | |
13. | ALA4264019 | F | Induction of NO release in human VSMC assessed as intracellular S-nitrosothiol level at 50 uM after 1 hr by fluorimetric method | Homo sapiens | 1 | ALA4261598 | cell-based format | Scientific Literature | |
14. | ALA4423895 | F | Antiproliferative activity against rat VSMC assessed as reduction in EdU incorporation after 24 hrs by Hoechst 33342 staining-based fluorescence assay | Rattus norvegicus | 1 | ALA4422642 | cell-based format | Scientific Literature | |
15. | ALA4423897 | F | Antimigratory activity in rat VSMC incubated for overnight followed by media replacement and measured every hour for 24 hrs by phase contrast microscopic analysis | Rattus norvegicus | 2 | ALA4422642 | cell-based format | Scientific Literature | |
16. | ALA4423927 | F | Antiproliferative activity against human VSMC assessed as reduction in EdU incorporation after 18 hrs by Hoechst 33342 staining-based fluorescence assay | Homo sapiens | 1 | ALA4422642 | cell-based format | Scientific Literature | |
17. | ALA4423928 | F | Antimigratory activity in human VSMC incubated for overnight followed by media replacement and measured every hour for 24 hrs by phase contrast microscopic analysis | Homo sapiens | 1 | ALA4422642 | cell-based format | Scientific Literature | |
18. | ALA4423933 | F | Antiproliferative activity against rat VSMC assessed as reduction in EdU incorporation after 18 hrs by Hoechst 33342 staining-based fluorescence assay | Rattus norvegicus | 1 | ALA4422642 | cell-based format | Scientific Literature | |
19. | ALA5142897 | T | Cytotoxicity against Wistar rat VSMCs assessed as reduction in cell viability at 50 uM incubated for 48 hrs by MTT assay | Rattus norvegicus | 1 | ALA5137108 | cell-based format | Scientific Literature | |
20. | ALA5232254 | T | Cytotoxicity against rat VSMC cells assessed as reduction in cell viability at 5 uM measured after 4 days | Rattus norvegicus | 1 | ALA5230142 | cell-based format | Scientific Literature |