| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4147114 | F | Inhibition of RANKL/mCSF-induced osteoclast differentiation in C57BL/6 mouse BMMC assessed as reduction in TRAP-positive multinucleated cells at 30 uM by microscopic method relative to control | Mus musculus | 5 | ALA4145488 | cell-based format | Scientific Literature | |
| 2. | ALA4147115 | F | Inhibition of RANKL/mCSF-induced osteoclast differentiation in C57BL/6 mouse BMMC assessed as reduction in TRAP-positive multinucleated cells by microscopic method | Mus musculus | 2 | ALA4145488 | cell-based format | Scientific Literature | |
| 3. | ALA4147116 | A | Cytotoxicity against C57BL/6 mouse BMMC up to 100 uM after 48 hrs by CCK8 assay | Mus musculus | 4 | ALA4145488 | cell-based format | Scientific Literature | |
| 4. | ALA4191401 | F | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse BMMC assessed as decrease in multinucleated TRAP+ cells after 3 days by TRAP staining-based assay | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 5. | ALA4191402 | F | Inhibition of M-CSF/RANKL-induced osteoclast differentiation in C57BL/6 mouse BMMC assessed as decrease in multinucleated TRAP+ cells at 20 uM after 3 days by TRAP staining-based assay | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 6. | ALA4191403 | A | Cytotoxicity against C57BL/6 mouse BMMC at 5 to 20 uM after 3 days in presence of M-CSF/RANKL by MTT assay | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 7. | ALA4191404 | F | Reduction in M-CSF/RANKL-induced NFATc1 mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 8. | ALA4191405 | F | Reduction in M-CSF/RANKL-induced Trap/Acp5 mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 9. | ALA4191406 | F | Reduction in M-CSF/RANKL-induced Itgb3 mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 10. | ALA4191407 | F | Reduction in M-CSF/RANKL-induced V-ATPase mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 11. | ALA4191408 | F | Reduction in M-CSF/RANKL-induced Ctsk mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 12. | ALA4191409 | F | Reduction in M-CSF/RANKL-induced MMP-9 mRNA levels in C57BL/6 mouse BMMC at 20 uM after 3 days by RT-qPCR analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 13. | ALA4191410 | F | Downregulation of M-CSF/RANKL-induced NFATc1 protein expression levels in C57BL/6 mouse BMMC after 3 days by Western blot analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 14. | ALA4191411 | F | Downregulation of M-CSF/RANKL-induced integrin alphaV protein expression levels in C57BL/6 mouse BMMC at 20 uM after 3 days by Western blot analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 15. | ALA4191412 | F | Downregulation of M-CSF/RANKL-induced CTSK protein expression levels in C57BL/6 mouse BMMC at 20 uM after 3 days by Western blot analysis | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 16. | ALA4191414 | F | Inhibition of M-CSF/RANKL-induced matrix resorption capacity in C57BL/6 mouse BMMC at 10 to 20 uM after 4 days in hydroxyapatite-coated plates | Mus musculus | 1 | ALA4190203 | cell-based format | Scientific Literature | |
| 17. | ALA4235264 | F | Antiproliferative activity against BALB/c mouse BMMC after 48 hrs by MTT assay | Mus musculus | 4 | ALA4229503 | cell-based format | Scientific Literature | |
| 18. | ALA4235265 | F | Antiinflammatory activity against BALB/c mouse BMMC assessed as reduction in TNFalpha levels incubated for 30 mins measured after 48 hrs by ELISA | Mus musculus | 2 | ALA4229503 | cell-based format | Scientific Literature | |
| 19. | ALA4671300 | A | Cytotoxicity against mouse BMMC assessed as reduction in cell viability at 5 uM measured after 48 hrs by MTT assay | Mus musculus | 3 | ALA4665827 | cell-based format | Scientific Literature | |
| 20. | ALA4671305 | A | Cytotoxicity against mouse BMMC assessed as reduction in cell viability measured after 48 hrs by MTT assay | Mus musculus | 46 | ALA4665827 | cell-based format | Scientific Literature |
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