# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1015340 | F | Inhibition of histamine-induced bronchospasm in guinea pig trachea by plethysmograph chamber assay | Cavia porcellus | 2 | ALA1153418 | tissue-based format | Scientific Literature | |
2. | ALA3253099 | F | Cholinolytic activity in guinea pig trachea at 2.94 X 10'-7 M to 1.176 X 10'-6 M in presence of acetylcholine | Cavia porcellus | 1 | ALA3243943 | tissue-based format | Scientific Literature | |
3. | ALA3256041 | F | Anticholinergic activity in guinea pig trachea assessed as carbamylcholine-induced constriction at 10 uM | Cavia porcellus | 1 | ALA3244175 | tissue-based format | Scientific Literature | |
4. | ALA4131853 | F | Induction of bronchodilation in guinea pig tracheal rings assessed as reduction in histamine-induced contractions | Cavia porcellus | 30 | ALA4130361 | tissue-based format | Scientific Literature | |
5. | ALA4131854 | F | Potency index, ratio of theophylline IC50 to test compound IC50 for reduction in histamine-induced contractions in guinea pig tracheal rings | Cavia porcellus | 1 | ALA4130361 | tissue-based format | Scientific Literature | |
6. | ALA4140046 | F | Inhibition of egg albumin antigen challenge-induced contraction response in methacholine-primed guinea pig trachea at 10 ug/ml | Cavia porcellus | 1 | ALA4138122 | tissue-based format | Scientific Literature | |
7. | ALA4140047 | F | Inhibition of egg albumin antigen challenge-induced contraction response in methacholine-primed guinea pig trachea at 3 ug/ml | Cavia porcellus | 1 | ALA4138122 | tissue-based format | Scientific Literature | |
8. | ALA4709015 | F | Vasorelaxant activity in OVA-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in absence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
9. | ALA4709017 | F | Vasorelaxant activity in OVA-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in presence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
10. | ALA4709018 | F | Vasorelaxant activity in non-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in absence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
11. | ALA4709019 | F | Vasorelaxant activity in non-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in presence of functional epithelium | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
12. | ALA5129837 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 3 nmol/Kg, IT(Intratracheal) measured after 1 hr by Konzett-Roessler methodology relative to control | Cavia porcellus | 3 | ALA5126603 | assay format | Scientific Literature | |
13. | ALA5129840 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 3 nmol/Kg, IT(Intratracheal) measured after 24 hr by Konzett-Roessler methodology relative to control | Cavia porcellus | 3 | ALA5126603 | assay format | Scientific Literature | |
14. | ALA5129842 | F | Invivo bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as time duration for inhibition of carbachol induced contraction measured upto 4 hrs | Cavia porcellus | 8 | ALA5126603 | tissue-based format | Scientific Literature | |
15. | ALA5129844 | F | Invivo bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of carbachol induced contraction | Cavia porcellus | 8 | ALA5126603 | tissue-based format | Scientific Literature | |
16. | ALA5129845 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 0.1 nmol/Kg, IT(Intratracheal) measured after 5 mins by Konzett-Roessler methodology relative to control | Cavia porcellus | 1 | ALA5126603 | assay format | Scientific Literature | |
17. | ALA5129846 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 0.1 nmol/Kg, IT(Intratracheal) measured after 15 mins by Konzett-Roessler methodology relative to control | Cavia porcellus | 1 | ALA5126603 | assay format | Scientific Literature | |
18. | ALA5129847 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 0.1 nmol/Kg, IT(Intratracheal) measured after 30 mins by Konzett-Roessler methodology relative to control | Cavia porcellus | 1 | ALA5126603 | assay format | Scientific Literature | |
19. | ALA5129848 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 0.3 nmol/Kg, IT(Intratracheal) measured after 5 mins by Konzett-Roessler methodology relative to control | Cavia porcellus | 1 | ALA5126603 | assay format | Scientific Literature | |
20. | ALA5129849 | F | Bifunctional antagonist activity at muscarinic M3 receptor /agonist activity at beta-2 adrenoceptor in Dunkin-Hartley guinea pig trachea assessed as inhibition of acetylcholine-induced bronchoconstriction at 0.3 nmol/Kg, IT(Intratracheal) measured after 15 mins by Konzett-Roessler methodology relative to control | Cavia porcellus | 1 | ALA5126603 | assay format | Scientific Literature |