| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4253042 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 1 post administration by hematoxylin-eosin-saffron staining based microscopic analysis (Rvb = 13 +/- 7%) | Homo sapiens | 1 | ALA4251585 | tissue-based format | Scientific Literature | |
| 2. | ALA4253043 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 2 post administration by hematoxylin-eosin-saffron staining based microscopic analysis (Rvb = 28 +/- 2%) | Homo sapiens | 1 | ALA4251585 | tissue-based format | Scientific Literature | |
| 3. | ALA4253044 | F | Induction of wound healing in human skin explant assessed as re-epithelialization at 5 uM administered topically for 3 days measured on day 3 post administration by hematoxylin-eosin-saffron staining based microscopic analysis relative to control | Homo sapiens | 1 | ALA4251585 | tissue-based format | Scientific Literature | |
| 4. | ALA4392657 | F | Induction of keratinocyte differentiation in human EPI-212 EpiDerm skin model assessed as increase in keratin-10 expression at 100 uM incubated for 7 days by DAB based immunohistochemical staining analysis (Rvb= 35.8%) | Homo sapiens | 1 | ALA4390697 | tissue-based format | Scientific Literature | |
| 5. | ALA4392658 | F | Induction of keratinocyte differentiation in human EPI-212 EpiDerm skin model assessed as increase in filaggrin expression at 100 uM incubated for 7 days by DAB based immunohistochemical staining analysis (Rvb= 20%) | Homo sapiens | 1 | ALA4390697 | tissue-based format | Scientific Literature | |
| 6. | ALA4614902 | F | Anti-aging activity in reconstructed human skin assessed as dermis contraction at 150 uM by hematoxylin and eosin staining-based microscopic analysis (Rvb = 57.4%) | Homo sapiens | 2 | ALA4613257 | tissue-based format | Scientific Literature | |
| 7. | ALA4614903 | F | Anti-aging activity in reconstructed human skin assessed as dermis contraction at 10 mM by hematoxylin and eosin staining-based microscopic analysis (Rvb = 57.4%) | Homo sapiens | 1 | ALA4613257 | tissue-based format | Scientific Literature |
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