# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3998900 | Functional | Anti-parasitic activity against bloodstream form of Trypanosoma congolense IL3000 after 48 hrs by alamar blue based fluorescence assay | Trypanosoma congolense | 20 | ALA3997795 | assay format | Scientific Literature | |
2. | ALA4139781 | Functional | Antiparasitic activity against Trypanosoma congolense IL3000 after 69 hrs by Alamar blue assay | Trypanosoma congolense | 19 | ALA4138115 | organism-based format | Scientific Literature | |
3. | ALA4231093 | Functional | Anti-parasitic activity against bloodstream form of Trypanosoma congolense IL3000 after 48 hrs by resazurin-based assay | Trypanosoma congolense | 27 | ALA4229345 | organism-based format | Scientific Literature | |
4. | ALA4231108 | Functional | Potency index, ratio of diminazene EC50 to test compound EC50 for anti-parasitic activity against bloodstream form of Trypanosoma congolense IL3000 | Trypanosoma congolense | 3 | ALA4229345 | organism-based format | Scientific Literature | |
5. | ALA4263514 | Functional | Antitrypanosomal activity against Trypanosoma congolense STIB 910 trypomastigotes after 24 hrs by Alamar Blue assay | Trypanosoma congolense | 1 | ALA4261582 | organism-based format | Scientific Literature | |
6. | ALA4424115 | Functional | Antitrypanosomal activity against Trypanosoma congolense by resazurin assay | Trypanosoma congolense | 5 | ALA4422651 | organism-based format | Scientific Literature | |
7. | ALA4427805 | Functional | Antitrypanosomal activity against Trypanosoma congolense IL3000 incubated for 48 hrs measured after 4 hrs | Trypanosoma congolense | 1 | ALA4425181 | organism-based format | Scientific Literature | |
8. | ALA4482205 | Functional | Trypanocidal activity against bloodstream form of Trypanosoma congolense IL3000 after 72 hrs by CellTiter-Glo reagent-based luminescence assay | Trypanosoma congolense | 18 | ALA4480459 | organism-based format | Scientific Literature | |
9. | ALA4728177 | Functional | Antitrypanosomal activity against blood form Trypanosoma congolense IL3000 incubated for 69 hrs by resazurin dye based assay | Trypanosoma congolense | 1 | ALA4725343 | organism-based format | Scientific Literature | |
10. | ALA4813525 | Functional | Trypanocidal activity against Trypanosoma congolense assessed as reduction in intracellular ATP production incubated for 72 hrs by CellTiter-Glo luminescent cell viability assay | Trypanosoma congolense | 50 | ALA4811303 | organism-based format | Scientific Literature | |
11. | ALA5050277 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 assessed as parasite growth inhibition incubated for 69 hrs by resazurin dye based fluorescence analysis | Trypanosoma congolense | 8 | ALA5046314 | organism-based format | Scientific Literature | |
12. | ALA5050288 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in NMRI mouse assessed as reduction in parasitemia at 10 mg/kg, sc BID for 4 days and measured twice a week for 21 days | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
13. | ALA5050289 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in NMRI mouse assessed as reduction in parasitemia at 50 mg/kg, sc administered as single dose for 4 days and measured twice a week for 21 days | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
14. | ALA5050306 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in NMRI mouse assessed as reduction in parasitemia at 10 mg/kg, sc administered once daily for 4 days | Trypanosoma congolense | 7 | ALA5046314 | organism-based format | Scientific Literature | |
15. | ALA5050310 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in NMRI mouse assessed as reduction in parasitemia at 3 mg/kg, sc administered for 4 days | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
16. | ALA5050311 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in Fulani Zebu cattle assessed as reduction in parasitemia at 10 mg/kg, IM administered as single dose monitered for 100 days | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
17. | ALA5050316 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense IL3000 infected in NMRI mouse assessed as reduction in parasitemia at 10 to 100 ng/ml administered via sc implanted ALZET osmotic pumps for 48 hrs | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
18. | ALA5050317 | Functional | Antitrypanosomal activity against bloodstream Trypanosoma congolense KONT 2/133 infected in Friesian-Holstein calf assessed as reduction in parasitemia at 5 mg/kg, sc BID and measured after 3 days | Trypanosoma congolense | 1 | ALA5046314 | organism-based format | Scientific Literature | |
19. | ALA5137249 | Functional | Antitrypanosomal activity against bloodstream form of Trypanosoma congolense IL3000 measured after 48 hrs by alamar blue assay | Trypanosoma congolense | 3 | ALA5136964 | organism-based format | Scientific Literature | |
20. | ALA5137253 | Functional | Antitrypanosomal activity against bloodstream form of diminazene-resistant Trypanosoma congolense DimR measured after 48 hrs by alamar blue assay | Trypanosoma congolense | 3 | ALA5136964 | organism-based format | Scientific Literature |