# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA940624 | B | Induction of FRB-FKBP complex interaction transfected in human HeLa cells assessed as split ubiquitin-C based rescue of caspase 3 activity at 100 nM by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
2. | ALA940625 | B | Induction of FRB-FKBP complex interaction transfected in human HeLa cells assessed as split ubiquitin-C based rescue of caspase-3 mutant activity at 100 nM by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
3. | ALA940626 | B | Induction of FRB-FKBP complex interaction transfected in SYF cells assessed as rescue of v-src activity from ubiquitin-C mediated degradation at 100 nM after 24 hrs by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
4. | ALA940627 | B | Induction of FRB-FKBP complex interaction transfected in SYF cells assessed as rescue of v-src stabilization mutant activity from ubiquitin-C mediated degradation at 100 nM after 24 hrs by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
5. | ALA940628 | B | Induction of FRB-FKBP complex interaction transfected in human HeLa cells assessed as rescue of Smad3 activity from ubiquitin-C mediated degradation at 100 nM after 24 hrs by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
6. | ALA940629 | B | Induction of FRB-FKBP complex interaction transfected in human HeLa cells assessed as rescue of Smad3 stabilization mutant activity from ubiquitin-C mediated degradation at 100 nM after 24 hrs by Western blot | 1 | ALA1156477 | cell-based format | Scientific Literature | ||
7. | ALA1646212 | B | Inhibition of human mTOR/FKBP12 at 10 uM after 60 mins by TR-FRET assay | Homo sapiens | 1 | ALA1641539 | protein complex format | Scientific Literature | |
8. | ALA3240781 | B | Inhibition of human mTOR/FKBP12 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | protein complex format | Scientific Literature | |
9. | ALA3777724 | B | Inhibition of N-terminal His6-tagged recombinant human MTOR/FKBP12 expressed in baculovirus infected insect Sf9 cells assessed as remaining activity at 1 uM relative to control | Homo sapiens | 3 | ALA3774357 | cell-based format | Scientific Literature | |
10. | ALA4023025 | B | Inhibition of full length recombinant human mTOR/FKBP12 | Homo sapiens | 1 | ALA4020823 | protein complex format | Scientific Literature | |
11. | ALA4881146 | B | mTOR/FKBP12(h) Eurofins Kinase panel | Homo sapiens | 1 | ALA4507268 | protein complex format | Donated Chemical Probes - SGC Frankfurt | |
12. | ALA4884401 | B | mTOR/FKBP12(h) Eurofins kinase panel | Homo sapiens | 1 | ALA4507319 | protein complex format | Donated Chemical Probes - SGC Frankfurt | |
13. | ALA4886271 | B | mechanistic target of rapamycin / FKBP12 Millipore kinase panel | Homo sapiens | 1 | ALA4800727 | protein complex format | Donated Chemical Probes - SGC Frankfurt | |
14. | ALA4887963 | B | mTOR FKBP12(h) Millipore kinase panel | Homo sapiens | 1 | ALA4800729 | protein complex format | Donated Chemical Probes - SGC Frankfurt |