| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA5250571 | F | Antiviral activity against SARS-CoV-2 strain BetaCov/Belgium/GHB-03021/2020 infected in African Vero-E6 tagged with GFP assessed as decrease in cytopathic effect measured after 72 hrs | Severe acute respiratory syndrome coronavirus 2 | 11 | organism-based format | Scientific Literature | ||
| 2. | ALA5250573 | F | Antiviral activity against SARS-CoV-2 strain BetaCov/Belgium/GHB-03021/2020 infected in African Vero-E6 tagged with GFP assessed as decrease in cytopathic effect in presence of CP100356 at 2 uM measured after 72 hrs | Severe acute respiratory syndrome coronavirus 2 | 11 | organism-based format | Scientific Literature | ||
| 3. | ALA5250619 | F | Antiviral activity against SARS-CoV-2 infected in African green monkey Vero cells assessed as reduction in viral replication pretreated with compound for 1 hr and subsequent viral infection for 2 hrs followed by replacement with fresh drug containing medium measured 72 hrs post infection by qRT-PCR analysis | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA5250620 | F | Antiviral activity against SARS-CoV-2/human/DEU/HH-1/2020 infected in African green monkey Vero E6 cells assessed as reduction in viral replication pretreated with compound for 1 hr and subsequent viral infection for 1 hr followed by replacement with fresh medium containing compounds measured 42 hrs post-infection by qRT-PCR analysis | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA5250624 | F | Antiviral activity against SARS-CoV-2 UC-1074 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by microscopic analysis | Severe acute respiratory syndrome coronavirus 2 | 5 | organism-based format | Scientific Literature | ||
| 6. | ALA5250625 | F | Antiviral activity against SARS-CoV-2 RG2674 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by microscopic analysis | Severe acute respiratory syndrome coronavirus 2 | 4 | organism-based format | Scientific Literature | ||
| 7. | ALA5250626 | F | Antiviral activity against SARS-CoV-2 NVDBB-2220 infected in African green monkey Vero cells assessed as reduction in virus-induced cytopathic effect incubated for 5 days by microscopic analysis | Severe acute respiratory syndrome coronavirus 2 | 4 | organism-based format | Scientific Literature | ||
| 8. | ALA5256307 | F | Antiviral activity against SARS-CoV-2 BetaCoV/France/IDF0372/2020 infected human A549-ACE2 cells assessed as inhibition of viral replication by qRT-PCR analysis | Severe acute respiratory syndrome coronavirus 2 | 22 | organism-based format | Scientific Literature | ||
| 9. | ALA5256309 | F | Antiviral activity against SARS-CoV-2 Omicron BA1 variant infected human A549-ACE2 cells assessed as inhibition of viral replication | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature | ||
| 10. | ALA5254920 | F | Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 cells assessed as reduction in infection measured after 24 hrs by Plaque assay | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature | ||
| 11. | ALA5254922 | F | Antiviral activity against SARS-CoV-2 infected in African green monkey Caco-2 cells | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA5254930 | F | Antiviral activity against SARS-CoV-2 infected in African green monkey Vero E6 cells | Severe acute respiratory syndrome coronavirus 2 | 2 | organism-based format | Scientific Literature | ||
| 13. | ALA5254959 | F | Antiviral activity against SARS-CoV-2 (hCoV-19/Korea/KCDC-06/2020) infected in African green monkey Vero cells preincubated with cells for 24 hrs followed by viral infection and measured after 24 hrs by DAPI-staining based fluorescence assay | Severe acute respiratory syndrome coronavirus 2 | 14 | organism-based format | Scientific Literature | ||
| 14. | ALA5254966 | F | Potency index, ratio of beta-D-N4-hydroxycytidine EC50 to test compound EC50 for antiviral activity against antiviral activity against SARS-CoV-2 (hCoV-19/Korea/KCDC-06/2020) infected in African green monkey Vero cells preincubated with cells for 24 hrs followed by viral infection and measured after 24 hrs by DAPI-staining based fluorescence assay | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA5254967 | F | Potency index, ratio of MK-4482 EC50 to test compound EC50 for antiviral activity against antiviral activity against SARS-CoV-2 (hCoV-19/Korea/KCDC-06/2020) infected in African green monkey Vero cells preincubated with cells for 24 hrs followed by viral infection and measured after 24 hrs by DAPI-staining based fluorescence assay | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA5254970 | F | Potency index, ratio of remdesivir EC50 to test compound EC50 for antiviral activity against SARS-CoV-2 (hCoV-19/Korea/KCDC-06/2020) infected in African green monkey Vero cells preincubated with cells for 24 hrs followed by viral infection and measured after 24 hrs by DAPI-staining based fluorescence assay | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA5255365 | F | Antiviral activity against Severe acute respiratory syndrome coronavirus 2 infected in Vero cells | Severe acute respiratory syndrome coronavirus 2 | 17 | organism-based format | Scientific Literature | ||
| 18. | ALA5255368 | F | Antiviral activity against Severe acute respiratory syndrome coronavirus 2 infected in NCI-H1299 cells overexpressing ACE2 | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA5252275 | F | Antiviral activity against SARS-CoV-2 B.1.1.7 infected in human Calu-3 cells assessed as inhibition of viral infection preincubated for 1 hr followed by viral infection measured after 48 hrs by Hoechst 33342 staining based analysis | Severe acute respiratory syndrome coronavirus 2 | 4 | organism-based format | Scientific Literature | ||
| 20. | ALA5252278 | F | Antiviral activity against SARS-CoV-2 B.1.1.7 infected in human Caco-2 cells assessed as inhibition of viral infection preincubated for 1 hr followed by viral infection measured after 48 hrs by Hoechst 33342 staining based analysis | Severe acute respiratory syndrome coronavirus 2 | 1 | organism-based format | Scientific Literature |
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