# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3997697 | Functional | Growth inhibition of mouse 4T1.2 cells up to 20000 nM after 48 hrs by MTT assay | Mus musculus | 1 | ALA3994676 | cell-based format | Scientific Literature | |
2. | ALA3997698 | Functional | Growth inhibition of mouse 4T1.2 cells up to 20000 nM encapsulated within cucurbit[8]uril after 48 hrs by MTT assay | Mus musculus | 1 | ALA3994676 | cell-based format | Scientific Literature | |
3. | ALA3997702 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in Balb/c mouse assessed as tumor growth inhibition at 2 mg/kg, iv administered twice weekly for 2 weeks | Mus musculus | 1 | ALA3994676 | organism-based format | Scientific Literature | |
4. | ALA3997703 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in Balb/c mouse assessed as tumor growth inhibition at 3 mg/kg, iv encapsulated within cucurbit[8]uril administered twice weekly for 2 weeks | Mus musculus | 1 | ALA3994676 | organism-based format | Scientific Literature | |
5. | ALA3997704 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in Balb/c mouse assessed as mouse survival time at 3 mg/kg, iv encapsulated within cucurbit[8]uril administered twice weekly for 2 weeks measured up to 33 days | Mus musculus | 1 | ALA3994676 | organism-based format | Scientific Literature | |
6. | ALA3997705 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in Balb/c mouse assessed as mouse survival rate at 2 mg/kg, iv administered twice weekly for 2 weeks measured up to 33 days (rvb = 30%) | Mus musculus | 1 | ALA3994676 | organism-based format | Scientific Literature | |
7. | ALA4421211 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse assessed as median disease latency time at 5 to 50 mg/kg/day for 10 days and measured up to 60 days after tumor inoculation | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
8. | ALA4421212 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse assessed as median disease latency time at 25 mg/kg/day for 10 days (Rvb =33 days) | Mus musculus | 2 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
9. | ALA4421297 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse assessed as median disease latency time at 50 mg/kg/day for 10 days (Rvb =40 days) | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
10. | ALA4421298 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse assessed as effect on tumor size at 25 mg/kg/day for 10 days | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
11. | ALA4421299 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse assessed as reduction in mean number of lung metastases at 25 mg/kg/day for 10 days measured at day 28 after tumor inoculation relative to control | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
12. | ALA4421300 | Functional | Antitumor activity against mouse 4T1.2 cells implanted in BALB/c mouse undergoing sham surgery without excising tumor on day 12 assessed as effect on mouse survival at 25 mg/kg/day for 10 days | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
13. | ALA4421301 | Functional | Inhibition of tumor induced vascular response in mouse 4T1.2 cells implanted BALB/c mouse assessed as reduction in blood vessel coverage at 25 mg/kg/day for 10 days by bright field microscopy | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
14. | ALA4421302 | Functional | Inhibition of tumor induced vascular response in mouse 4T1.2 cells implanted BALB/c mouse assessed as reduction in number of endothelial cells in tumor region at 25 mg/kg/day for 10 days by ERG/EMCN-detection based immunofluorescent staining relative to control | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
15. | ALA4421303 | Functional | Inhibition of tumor induced vascular response in mouse 4T1.2 cells implanted BALB/c mouse assessed as reduction in volume of the blood vessels in tumor region at 25 mg/kg/day for 10 days by ERG/EMCN-detection based immunofluorescent staining relative to control | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
16. | ALA4421304 | Functional | Inhibition of tumor induced lymphangiogenesis response in mouse 4T1.2 cells implanted BALB/c mouse assessed as reduction in tumor associated lymphatic vessels at 25 mg/kg/day for 10 days by PROX1/podoplanin detection based immunofluorescent staining relative to control | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data | |
17. | ALA4421305 | Functional | Inhibition of tumor induced lymphangiogenesis response in mouse 4T1.2 cells implanted BALB/c mouse assessed as reduction in number of lymphatic endothelial cells at 25 mg/kg/day for 10 days by PROX1/podoplanin detection based immunofluorescent staining relative to control | Mus musculus | 1 | ALA4420080 | organism-based format | Patent Bioactivity Data |