| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1016381 | Functional | Induction of apoptosis in human 518A2 cells at 10 uM after 15 hrs by TUNEL assay | Homo sapiens | 1 | ALA1139368 | cell-based format | Scientific Literature | |
| 2. | ALA1016383 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase in cleaved/activated form of caspase 3 at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1139368 | cell-based format | Scientific Literature | |
| 3. | ALA1016384 | Functional | Induction of apoptosis in human 518A2 cells assessed as PARP cleavage at 1 uM after 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1139368 | cell-based format | Scientific Literature | |
| 4. | ALA1121146 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 8 activity at 5 uM measured up to 12 hrs by luminometric assay | Homo sapiens | 2 | ALA1157852 | cell-based format | Scientific Literature | |
| 5. | ALA1121147 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 3 activity at 5 uM measured up to 12 hrs by luminometric assay | Homo sapiens | 2 | ALA1157852 | cell-based format | Scientific Literature | |
| 6. | ALA1121148 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 9 activity at 5 uM after 8 to 12 hrs by luminometric assay | Homo sapiens | 2 | ALA1157852 | cell-based format | Scientific Literature | |
| 7. | ALA1121152 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 8 activity at 5 uM after 6 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 8. | ALA1121153 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 3 activity at 5 uM after 8 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 9. | ALA1121210 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 3 activity at 5 uM after 1 to 24 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 10. | ALA1121211 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 8 activity at 5 uM after 1 to 24 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 11. | ALA1121212 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 9 activity at 5 uM after 1 to 24 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 12. | ALA1121216 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 9 activity at 5 uM after 2 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 13. | ALA1121217 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 3 activity at 5 uM measured up to 24 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 14. | ALA1121218 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of caspase 8 activity at 5 uM measured up to 24 hrs by luminometric assay | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 15. | ALA1121220 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of ratio of Bax to Bcl-2 mRNA expression at 5 uM after 6 to 18 hrs by RT-PCR analysis | Homo sapiens | 5 | ALA1157852 | cell-based format | Scientific Literature | |
| 16. | ALA1121223 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of Bcl-2 mRNA expression at 5 uM up to 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 17. | ALA1121224 | Functional | Induction of apoptosis in human 518A2 cells assessed as increase of Bax mRNA expression at 5 uM up to 24 hrs by Western blot analysis | Homo sapiens | 1 | ALA1157852 | cell-based format | Scientific Literature | |
| 18. | ALA1121225 | Functional | Induction of apoptosis in human 518A2 cells assessed as appearance of intact mitochondria in cytosol at 5 uM after 6 hrs using JC1 dye relative to control | Homo sapiens | 10 | ALA1157852 | mitochondrion format | Scientific Literature | |
| 19. | ALA1121226 | Functional | Induction of apoptosis in human 518A2 cells assessed as appearance of intact mitochondria in cytosol at 5 uM after 18 hrs using JC1 dye relative to control | Homo sapiens | 10 | ALA1157852 | mitochondrion format | Scientific Literature | |
| 20. | ALA1250574 | Functional | Induction of apoptosis in human 518A2 cells assessed as ROS production at 50 uM after 24 hrs by NBT reduction assay relative to control | Homo sapiens | 12 | ALA1250515 | cell-based format | Scientific Literature |
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