# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4020456 | F | Antiproliferative activity against human A549/CDDP cells assessed as decrease in cell viability preincubated for 2 hrs followed by addition of 40 uM CDDP addition measured after 24 hrs by tetrazolium-dye based assay | Homo sapiens | 2 | ALA4017540 | cell-based format | Scientific Literature | |
2. | ALA4020457 | F | Antiproliferative activity against human A549/CDDP cells assessed as decrease in cell viability at 10 to 20 uM after 96 hrs in presence of 0.5 uM CDDP by tetrazolium-dye based assay | Homo sapiens | 2 | ALA4017540 | cell-based format | Scientific Literature | |
3. | ALA4020458 | F | Antimetastatic activity in human A549/CDDP cells at 10 to 20 uM after 48 hrs by boyden chamber method | Homo sapiens | 2 | ALA4017540 | cell-based format | Scientific Literature | |
4. | ALA4020459 | F | Antiinvasive activity in human A549/CDDP cells at 10 to 20 uM after 48 hrs by boyden chamber method | Homo sapiens | 2 | ALA4017540 | cell-based format | Scientific Literature | |
5. | ALA4024143 | F | Growth inhibition of human A549/CDDP cells after 48 hrs by MTT assay | Homo sapiens | 6 | ALA4020840 | cell-based format | Scientific Literature | |
6. | ALA4041261 | F | Antiproliferative activity against human A549/CDDP cells after 48 hrs by MTT assay | Homo sapiens | 2 | ALA4038345 | cell-based format | Scientific Literature | |
7. | ALA4330423 | F | Antiproliferative activity against human A549/CDDP cells after 72 hrs by MTT assay | Homo sapiens | 3 | ALA4330059 | cell-based format | Scientific Literature | |
8. | ALA4343284 | F | Antiproliferative activity against human A549/CDDP cells assessed as reduction in cell viability after 72 hrs by MTT assay | Homo sapiens | 2 | ALA4342418 | cell-based format | Scientific Literature | |
9. | ALA4428217 | F | Antiproliferative activity against human A549/CDDP cells after 72 hrs by MTT assay | Homo sapiens | 23 | ALA4428026 | cell-based format | Scientific Literature | |
10. | ALA4428219 | F | Induction of ROS generation in human A549/CDDP cells 2.1 to 4.2 uM after 60 mins by DHE staining-based fluorescence assay | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
11. | ALA4428228 | F | Decrease in TrxR expression in human A549/CDDP cells at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
12. | ALA4428230 | F | Decrease in Trx expression in human A549/CDDP cells at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
13. | ALA4428232 | F | Induction of ROS generation in human A549/CDDP cells 0.6 to 1.2 uM after 60 mins by DHE staining-based fluorescence assay in presence of NAC | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
14. | ALA4428233 | F | Induction of ROS generation in human A549/CDDP cells 0.6 to 1.2 uM after 60 mins by DHE staining-based fluorescence assay in presence of GSH | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
15. | ALA4428235 | F | Induction of apoptosis in human A549/CDDP cells at 0.6 to 1.2 uM after 24 hrs by annexin V-FITC/propidium iodide staining-based flow cytometry | Homo sapiens | 3 | ALA4428026 | cell-based format | Scientific Literature | |
16. | ALA4428238 | F | Induction of apoptosis in human A549/CDDP cells assessed as decrease in Bcl2 expression at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
17. | ALA4428239 | F | Induction of apoptosis in human A549/CDDP cells assessed as increase in Bax expression at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
18. | ALA4428241 | F | Induction of apoptosis in human A549/CDDP cells assessed as increase in Bax to Bcl2 ratio at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
19. | ALA4428243 | F | Induction of apoptosis in human A549/CDDP cells assessed as increase in cleaved caspase 3 level at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature | |
20. | ALA4428245 | F | Induction of apoptosis in human A549/CDDP cells assessed as increase in cleaved PARP level at 0.6 to 1.2 uM after 24 hrs by Western blot method | Homo sapiens | 1 | ALA4428026 | cell-based format | Scientific Literature |