# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4341647 | F | Cytotoxicity against mouse B16F10Nex2 cells assessed as reduction in cell viability incubated for 16 hrs by MTT assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
2. | ALA4341656 | F | Antitumor activity against mouse B16F10Nex2 cells transplanted in C57BL/6 mouse assessed as reduction in lungs superficial nodules at 20 uM, ip administered every other day for 12 days and measured 21 days post transplantation relative to control | Mus musculus | 2 | ALA4340535 | organism-based format | Scientific Literature | |
3. | ALA4341660 | F | Inhibition of cell adhesion of mouse B16F10Nex2 cells assessed as reduction in cell adhesion to type 1 collagen at 2 uM incubated for 3 hrs by toluidine blue staining based assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
4. | ALA4341661 | F | Inhibition of cell adhesion of mouse B16F10Nex2 cells assessed as reduction in cell adhesion to type 4 collagen at 2 uM incubated for 3 hrs by toluidine blue staining based assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
5. | ALA4341662 | F | Inhibition of cell adhesion of mouse B16F10Nex2 cells assessed as reduction in cell adhesion to fibronectin at 2 uM incubated for 3 hrs by toluidine blue staining based assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
6. | ALA4341663 | F | Inhibition of cell adhesion of mouse B16F10Nex2 cells assessed as reduction in cell adhesion to laminin at 2 uM incubated for 3 hrs by toluidine blue staining based assay | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
7. | ALA4341664 | F | Antimigratory activity against mouse B16F10Nex2 cells assessed as reduction in cell migration towards wound area at 20 uM measured every hour for 24 hrs by scratch wound-healing assay relative to control | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
8. | ALA4341667 | F | Anti-invasive activity in mouse B16F10Nex2 cells assessed as reduction in invasive potential at 20 uM incubated for 24 hrs by Giemsa staining based matrigel assay relative to control | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
9. | ALA4341668 | F | Induction of morphological changes in mouse B16F10Nex2 cells at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
10. | ALA4341670 | F | Induction of morphological changes in mouse B16F10Nex2 cells assessed as cell rounding at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
11. | ALA4341671 | F | Induction of morphological changes in mouse B16F10Nex2 cells assessed as retraction of cell protrusions at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
12. | ALA4341672 | F | Induction of morphological changes in mouse B16F10Nex2 cells assessed as depolymerisation of F-actin at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
13. | ALA4341673 | F | Induction of morphological changes in mouse B16F10Nex2 cells assessed as membrane blebbing at 10 uM incubated for 24 hrs by tubulin-Cy2 and TOPRO-3 staining based confocal microscopic method | Mus musculus | 2 | ALA4340535 | cell-based format | Scientific Literature | |
14. | ALA4341678 | F | Antitumor activity against mouse B16F10Nex2 cells transplanted in C57BL/6 mouse assessed as reduction in lung metastases at 20 uM, ip administered for 5 non-consecutive days and measured 21 days post transplantation relative to control | Mus musculus | 2 | ALA4340535 | organism-based format | Scientific Literature |