| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3386965 | F | Induction of cell differentiation in human BE(2)-C cells assessed as neurite outgrowth at 2 uM by CCK-8 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3386967 | F | Induction of cell differentiation in human BE(2)-C cells assessed as increase in acetylated tubulin at 2 to 10 uM after 24 hrs by immunoblot method relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 3. | ALA3386968 | F | Induction of cell differentiation in human BE(2)-C cells assessed as increase in TrkA expression at 2 to 10 uM after 24 hrs by immunoblot method relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 4. | ALA3386969 | F | Induction of HDAC6 expression in human BE(2)-C cells at 10 uM after 24 hrs by immunoblot method relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3386970 | F | Effect on p21 expression in human BE(2)-C cells at 10 uM after 24 hrs by immunoblot method relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3386971 | F | Effect on acetylated histone H3 expression in human BE(2)-C cells at 10 uM after 24 hrs by immunoblot method relative to vehicle-treated control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA4001133 | F | Growth inhibition of human BE(2)-C cells after 72 hrs by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4001163 | F | Growth inhibition of human BE(2)-C cells assessed as cell death at 25 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4027158 | F | Cytotoxicity against human BE(2)-C cells assessed as reduction in clonogenic growth at 10 uM administered for 96 hrs followed by 6 days growth time in absence of compound treatment by crystal violet-based assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 10. | ALA4027171 | F | Induction of outgrowth of neurofilament positive neutrite-like structures in human BE(2)-C cells at 10 uM after 6 days by DAPI-staining based microscopic analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA4027182 | F | Cytotoxicity against human BE(2)-C cells assessed as reduction in cell viability by measuring metabolic activity after 72 hrs by WST-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 12. | ALA4027190 | F | Induction of outgrowth of neurofilament positive neutrite-like structures in human BE(2)-C cells at 6 uM after 6 days by DAPI-staining based microscopic analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4343854 | F | Induction of apoptosis in human BE(2)-C cells assessed as apoptotic cells at 300 uM after 72 hrs by Annexin V-FITC/propidium iodide staining based flow cytometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4357185 | F | Antiproliferative activity against human BE(2)-C cells assessed as reduction in cell viability after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 15. | ALA4357187 | F | Antiproliferative activity against human BE(2)-C cells assessed as reduction in cell viability at 1000 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4357190 | F | Antiproliferative activity against human BE(2)-C cells assessed as reduction in cell viability in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA4357191 | F | Potentiation of cisplatin-induced cytotoxicity against human BE(2)-C cells assessed as cisplatin IC50 after 48 hrs by MTT assay (Rvb = 5.3 +/- 0.1 microM) | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 18. | ALA4357193 | F | Synergistic antiproliferative activity against human BE(2)-C cells assessed as FICI in presence of cisplatin after 48 hrs by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 19. | ALA4357196 | F | Ratio of IC50 for antiproliferative activity against human BE(2)-C cells to IC50 for antiproliferative activity against human BE(2)-C cells in presence of cisplatin | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4357199 | F | Antiproliferative activity against human BE(2)-C cells assessed as cell viability at 10.3 uM after 48 hrs by MTT assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature |
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