# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4031055 | A | Prodrug activation in human GRANTA-519 cells assessed as 9-((2R,3R,4S,5R)-5-(((((2-(1H-Indol-3-yl)ethyl)amino)-(hydroxy)phosphoryl)oxy)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)-2-amino-7-(2-(4-chlorophenoxy)ethyl)-6-oxo-6,9-dihydro-1H-purin-7-ium formation per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis | Homo sapiens | 1 | ALA4028857 | cell-based format | Scientific Literature | |
2. | ALA4031061 | A | Drug uptake in human GRANTA-519 cells assessed per 5 million cells at 150 uM after 12 hrs by LC-MS/MS analysis | Homo sapiens | 1 | ALA4028857 | cell-based format | Scientific Literature | |
3. | ALA4031066 | F | Antiproliferative activity against human GRANTA-519 cells preincubated for 48 hrs followed by thymidine addition measure after 16 hrs by Thymidine incorporation assay | Homo sapiens | 1 | ALA4028857 | cell-based format | Scientific Literature | |
4. | ALA4031068 | F | Antiproliferative activity against human GRANTA-519 cells at 200 uM preincubated for 48 hrs followed by thymidine addition measure after 16 hrs by Thymidine incorporation assay | Homo sapiens | 1 | ALA4028857 | cell-based format | Scientific Literature | |
5. | ALA4031070 | F | Antiproliferative activity against human GRANTA-519 cells after 48 hrs by Annexin V/propidium iodide based flow cytometric analysis | Homo sapiens | 1 | ALA4028857 | cell-based format | Scientific Literature | |
6. | ALA4220046 | F | Antiproliferative activity against human GRANTA-519 cells | Homo sapiens | 1 | ALA4219046 | cell-based format | Scientific Literature | |
7. | ALA4307075 | F | Antiproliferative activity against human GRANTA-519 cells assessed as reduction in cell viability supplemented with fresh medium containing compound every 3 days incubated for 10 days by CCK-8 assay | Homo sapiens | 6 | ALA4304780 | cell-based format | Scientific Literature | |
8. | ALA4307079 | F | Antiproliferative activity against human GRANTA-519 cells assessed as reduction in cell viability at 0.3 to 1 uM supplemented with fresh medium containing compound every 3 days incubated for 10 days by CCK-8 assay | Homo sapiens | 1 | ALA4304780 | cell-based format | Scientific Literature | |
9. | ALA4381268 | F | Antiproliferative activity against human GRANTA-519 cells assessed as reduction in cell viability at 10 uM incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
10. | ALA4381287 | F | Antiproliferative activity against human GRANTA-519 cells assessed as reduction in cell viability incubated for 48 hrs by cell titer-glo assay | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
11. | ALA4381328 | F | Induction of apoptosis in human GRANTA-519 cells assessed as increase in caspase-3/7 activation at 10 uM incubated for 48 hrs by luminometric caspase-glo 3/7 assay | Homo sapiens | 2 | ALA4376884 | cell-based format | Scientific Literature | |
12. | ALA4390290 | F | Antiproliferative activity against human GRANTA-519 cells assessed as reduction in viability after 72 hrs by CellTiter-Glo luminescent assay | Homo sapiens | 15 | ALA4387761 | cell-based format | Scientific Literature | |
13. | ALA4392559 | F | Antiproliferative activity against human GRANTA-519 cells incubated for 3 days and measured upto 10 days by CCK-8 assay | Homo sapiens | 2 | ALA4390690 | cell-based format | Scientific Literature | |
14. | ALA4886657 | F | Granta 519 cell line Proliferation assay | Homo sapiens | 1 | ALA4507259 | cell-based format | Donated Chemical Probes - SGC Frankfurt | |
15. | ALA5146378 | F | Anti-tumor activity against human Granta-519 cells assessed as inhibition of cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 3 | ALA5143613 | cell-based format | Scientific Literature | |
16. | ALA5159406 | F | Antiproliferative activity against ATM-deficient human Granta-519 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay | Homo sapiens | 1 | ALA5154749 | cell-based format | Scientific Literature | |
17. | ALA5225374 | F | Antiproliferative activity against human Granta-519 cells assessed as cell viability by non-radioactive cell proliferation MTT assay | Homo sapiens | 1 | ALA5223150 | cell-based format | Scientific Literature | |
18. | ALA5261822 | F | Cytotoxicity against human Granta-519 cells measured after 8 days | Homo sapiens | 3 | ALA5260810 | cell-based format | Scientific Literature | |
19. | ALA5262609 | F | Cytotoxicity against human Granta-519 cells measured after 3 days | Homo sapiens | 1 | ALA5260810 | cell-based format | Scientific Literature |